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The Study of Serum Vitamin D and Insulin Resistance in Chinese Populations with Normal Glucose Tolerance
Joint Authors
Ding, Lin
Pang, Shuguang
Tian, Yuling
Wang, Congcong
Ma, Heliang
Lu, Yong
Source
International Journal of Endocrinology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-01
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Objectives.
The aim of this study was to investigate the relationship between serum vitamin D and insulin resistance in Chinese subjects without diabetes mellitus.
Methods.
Serum 25(OH)D was measured in 897 individuals with normal glucose tolerance (NGT).
Oral glucose tolerance tests (OGTTs) were conducted to exclude cases with diabetes, impaired fasting glucose (IFG), and impaired glucose tolerance (IGT).
Metabolic parameters were measured and compared between the highest and lowest 25(OH)D quartiles.
The relationship between serum 25(OH)D and homeostatic model assessment-insulin resistance (HOMA-IR) was analyzed.
Results.
Indexes, such as HOMA-IR, FINS, and SBP, were negatively correlated with serum 25(OH)D concentrations.
Compared with the lowest quartile, individuals in the highest group had decreased Lg (HOMA-IR), Lg (FINS), and SBP.
Pearson correlation analyses showed that serum 25(OH)D was negatively associated with age, BMI, Lg (HOMA-IR), and Lg (FINS).
Multivariate linear regression analysis confirmed the negative correlation of Lg (HOMA-IR) and 25(OH)D.
Conclusions.
This study showed that serum 25(OH)D could be regarded as an independent predictor of insulin resistance for subjects without diabetes mellitus in China.
Adequate vitamin D supplementation may improve multiple metabolic disturbances.
American Psychological Association (APA)
Ding, Lin& Wang, Congcong& Ma, Heliang& Tian, Yuling& Lu, Yong& Pang, Shuguang. 2014. The Study of Serum Vitamin D and Insulin Resistance in Chinese Populations with Normal Glucose Tolerance. International Journal of Endocrinology،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1036608
Modern Language Association (MLA)
Ding, Lin…[et al.]. The Study of Serum Vitamin D and Insulin Resistance in Chinese Populations with Normal Glucose Tolerance. International Journal of Endocrinology No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-1036608
American Medical Association (AMA)
Ding, Lin& Wang, Congcong& Ma, Heliang& Tian, Yuling& Lu, Yong& Pang, Shuguang. The Study of Serum Vitamin D and Insulin Resistance in Chinese Populations with Normal Glucose Tolerance. International Journal of Endocrinology. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1036608
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1036608