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Selenium Supplementation for Autoimmune Thyroiditis: A Systematic Review and Meta-Analysis
Joint Authors
Fan, Yaofu
Xu, Shuhang
Zhang, Huifeng
Cao, Wen
Wang, Kun
Chen, Guofang
Di, Hongjie
Cao, Meng
Liu, Chao
Source
International Journal of Endocrinology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-11
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Many studies have reported that selenium (Se) has a close relationship with autoimmune thyroiditis (AIT).
The therapeutic effect of Se supplementation in AIT treatment remains unclear.
The objective of the present study was to determine the efficacy of Se supplementation for the treatment of AIT.
A structured literature search was undertaken to identify all randomized controlled trials conducted in patients with AIT receiving Se supplementation or placebo.
Nine studies enrolling a total of 787 patients were included.
The results showed that Se supplementation with duration 6 months significantly dropped the TPOAb titers but did not decrease the TgAb titers.
Patients assigned to Se supplementation for 12-month duration showed significantly lower TPOAb titers and TgAb titers.
Patients after Se supplementation had a higher chance to improve the mood or well-being compared with controls.
Se supplementation is associated with a significant decrease in TPOAb titers at 6 and 12 months; meanwhile, the TgAb titers can be dropped at 12 months.
After Se supplementation treatment, patients had a higher chance to improve the mood without significant adverse events.
American Psychological Association (APA)
Fan, Yaofu& Xu, Shuhang& Zhang, Huifeng& Cao, Wen& Wang, Kun& Chen, Guofang…[et al.]. 2014. Selenium Supplementation for Autoimmune Thyroiditis: A Systematic Review and Meta-Analysis. International Journal of Endocrinology،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1036614
Modern Language Association (MLA)
Fan, Yaofu…[et al.]. Selenium Supplementation for Autoimmune Thyroiditis: A Systematic Review and Meta-Analysis. International Journal of Endocrinology No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1036614
American Medical Association (AMA)
Fan, Yaofu& Xu, Shuhang& Zhang, Huifeng& Cao, Wen& Wang, Kun& Chen, Guofang…[et al.]. Selenium Supplementation for Autoimmune Thyroiditis: A Systematic Review and Meta-Analysis. International Journal of Endocrinology. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1036614
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1036614