Retrospective Analysis of Cushing’s Disease with or without Hyperprolactinemia
Joint Authors
Huan, Cheng
Lu, Chao
Xu, Guang-ming
Qu, Xin
Qu, Yuan-ming
Source
International Journal of Endocrinology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-23
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objective.
We compared the characteristics of patients with Cushing’s disease alone with those of patients with Cushing’s disease and hyperprolactinemia.
Methods.
Eighty-four patients were enrolled between 2002 and 2011, in a hospital in China.
Clinical, endocrinological, and histopathological data, MRI scans, and surgical outcomes were reviewed throughout the follow-up period.
Results.
Patients with Cushing’s disease and hyperprolactinemia had a younger age at diagnosis (30.28 ± 14.23 versus 36.08 ± 10.91 years; P=0.037) and a larger adenoma maximal diameter (2.44 ± 1.32 versus 1.44 ± 1.05 cm; P<0.001) than patients with Cushing’s disease alone.
Menstrual disorders (P=0.027) and visual field defects (P=0.021) were more common and progressive obesity (P=0.009) and hypertension (P<0.001) were less common in patients with Cushing’s disease and hyperprolactinemia.
The rate of normalization of hormonal levels was lower (41.7% versus 91.7%; P<0.001) and the recurrence rate was higher (36.1% versus 8.3%; P<0.001) in patients with Cushing’s disease and hyperprolactinemia.
Conclusions.
Careful long-term follow-up is needed of patients with Cushing’s disease and hyperprolactinemia.
American Psychological Association (APA)
Huan, Cheng& Lu, Chao& Xu, Guang-ming& Qu, Xin& Qu, Yuan-ming. 2014. Retrospective Analysis of Cushing’s Disease with or without Hyperprolactinemia. International Journal of Endocrinology،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1036620
Modern Language Association (MLA)
Huan, Cheng…[et al.]. Retrospective Analysis of Cushing’s Disease with or without Hyperprolactinemia. International Journal of Endocrinology No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1036620
American Medical Association (AMA)
Huan, Cheng& Lu, Chao& Xu, Guang-ming& Qu, Xin& Qu, Yuan-ming. Retrospective Analysis of Cushing’s Disease with or without Hyperprolactinemia. International Journal of Endocrinology. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1036620
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1036620