New Insight into the Molecular Drug Target of Diabetic Nephropathy
Joint Authors
Louisa, Melva
Setiabudy, Rianto
Soetikno, Vivian
Arozal, Wawaimuli
Source
International Journal of Endocrinology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-04
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Diabetic nephropathy (DN) lowered quality of life and shortened life expectancy amongst those affected.
Evidence indicates interaction between advanced glycation end products (AGEs), activated protein kinase C (PKC) and angiotensin II exacerbate the progression of DN.
Inhibitors of angiotensin-converting enzyme (ACEIs), renin angiotensin aldosterone system (RAAS), AGEs, and PKC have been tested for slowing down the progression of DN.
The exact molecular drug targets that lead to the amelioration of renal injury in DN are not well understood.
This review summarizes the potential therapeutic targets, based on putative mechanism in the progression of the disease.
American Psychological Association (APA)
Soetikno, Vivian& Arozal, Wawaimuli& Louisa, Melva& Setiabudy, Rianto. 2014. New Insight into the Molecular Drug Target of Diabetic Nephropathy. International Journal of Endocrinology،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1036633
Modern Language Association (MLA)
Soetikno, Vivian…[et al.]. New Insight into the Molecular Drug Target of Diabetic Nephropathy. International Journal of Endocrinology No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1036633
American Medical Association (AMA)
Soetikno, Vivian& Arozal, Wawaimuli& Louisa, Melva& Setiabudy, Rianto. New Insight into the Molecular Drug Target of Diabetic Nephropathy. International Journal of Endocrinology. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1036633
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1036633
