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High Salt Intake Increases Copeptin but Salt Sensitivity Is Associated with Fluid Induced Reduction of Copeptin in Women
Joint Authors
Tasevska, Irina
Enhörning, Sofia
Burri, Philippe
Melander, Olle
Source
International Journal of Hypertension
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-10-22
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
This study investigated if copeptin is affected by high salt intake and whether any salt-induced changes in copeptin are related to the degree of salt sensitivity.
The study was performed on 20 men and 19 women.
In addition to meals containing 50 mmol NaCl daily, capsules containing 100 mmol NaCl and corresponding placebo capsules were administered during 4 weeks each, in random order.
Measurements of 24 h blood pressure, body weight, 24 h urinary volume, and fasting plasma copeptin were performed at high and low salt consumption.
Copeptin increased after a high compared to low dietary salt consumption in all subjects 3,59 ± 2,28 versus 3,12 ± 1,95 (P = 0,02).
Copeptin correlated inversely with urinary volume, at both low (r = −0,42; P = 0,001) and high (r = −0,60; P < 0,001) salt consumption, as well as with the change in body weight (r = −0,53; P < 0,001).
Systolic salt sensitivity was inversely correlated with salt-induced changes of copeptin, only in females (r = −0,58; P = 0,017).
As suppression of copeptin on high versus low salt intake was associated with systolic salt sensitivity in women, our data suggest that high fluid intake and fluid retention may contribute to salt sensitivity.
American Psychological Association (APA)
Tasevska, Irina& Enhörning, Sofia& Burri, Philippe& Melander, Olle. 2014. High Salt Intake Increases Copeptin but Salt Sensitivity Is Associated with Fluid Induced Reduction of Copeptin in Women. International Journal of Hypertension،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1036716
Modern Language Association (MLA)
Tasevska, Irina…[et al.]. High Salt Intake Increases Copeptin but Salt Sensitivity Is Associated with Fluid Induced Reduction of Copeptin in Women. International Journal of Hypertension No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1036716
American Medical Association (AMA)
Tasevska, Irina& Enhörning, Sofia& Burri, Philippe& Melander, Olle. High Salt Intake Increases Copeptin but Salt Sensitivity Is Associated with Fluid Induced Reduction of Copeptin in Women. International Journal of Hypertension. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1036716
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1036716