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Duration of Electrically Induced Atrial Fibrillation Is Augmented by High Voltage of Stimulus with Higher Blood Pressure in Hypertensive Rats
Joint Authors
Hirooka, Yoshitaka
Nagayama, Tomomi
Chishaki, Akiko
Takemoto, Masao
Mukai, Yasushi
Inoue, Shujiro
Sunagawa, Kenji
Kishi, Takuya
Source
International Journal of Hypertension
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-25
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
Many previous clinical studies have suggested that atrial fibrillation (AF) is closely associated with hypertension.
However, the benefits of antihypertensive therapy on AF are still inconsistent, and it is necessary to explore the factors augmenting AF in hypertensive rats.
The aim of the present study was to investigate the correlation between arterial pressure or voltage stimulus and to the duration of electrically induced AF in normotensive or hypertensive rats.
Methods.
AF was reproducibly induced by transesophageal atrial burst pacing in spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY).
We did the burst pacing at high (20 V) or low (5 V) voltage.
Results.
Duration of AF did not correlate with systolic blood pressure (SBP) and stimulus voltage in WKY.
However, only in SHR, duration of AF with high stimulus voltage significantly correlated with SBP and was significantly longer in high than in low voltage stimulus.
Discussion and Conclusion.
Duration of AF is augmented by high voltage stimulus with higher blood pressure in SHR.
American Psychological Association (APA)
Nagayama, Tomomi& Hirooka, Yoshitaka& Chishaki, Akiko& Takemoto, Masao& Mukai, Yasushi& Inoue, Shujiro…[et al.]. 2014. Duration of Electrically Induced Atrial Fibrillation Is Augmented by High Voltage of Stimulus with Higher Blood Pressure in Hypertensive Rats. International Journal of Hypertension،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1036722
Modern Language Association (MLA)
Nagayama, Tomomi…[et al.]. Duration of Electrically Induced Atrial Fibrillation Is Augmented by High Voltage of Stimulus with Higher Blood Pressure in Hypertensive Rats. International Journal of Hypertension No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1036722
American Medical Association (AMA)
Nagayama, Tomomi& Hirooka, Yoshitaka& Chishaki, Akiko& Takemoto, Masao& Mukai, Yasushi& Inoue, Shujiro…[et al.]. Duration of Electrically Induced Atrial Fibrillation Is Augmented by High Voltage of Stimulus with Higher Blood Pressure in Hypertensive Rats. International Journal of Hypertension. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1036722
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1036722