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Annual Decline in Pentraxin 3 Is a Risk of Vascular Access Troubles in Hemodialysis Patients
Joint Authors
Nagai, Kei
Ueda, Atsushi
Saito, Chie
Zempo-Miyaki, Asako
Yamagata, Kunihiro
Source
International Journal of Nephrology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-21
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Pentraxin 3 (PTX3), a multifunctional modulator of the innate immunoinflammatory response, is higher in patients undergoing hemodialysis than healthy control.
Our study focused on annual change in PTX3 levels in patients with chronic hemodialysis, because regularly undergoing hemodialysis for many years modifies vascular inflammatory status.
To demonstrate whether annual change in PTX3 is associated with vascular events, we measured blood levels of pentraxins (PTX3 and high-sensitivity C-reactive protein (hsCRP)) at baseline and in the next year in 76 hemodialysis patients and observed 20 patients with vascular access troubles during follow-up years.
The annual decline in PTX3, but not hsCRP, is a significant risk of the incidence of vascular access trouble that is a critical and specific complication for hemodialysis patients (hazard ratio; 0.732 per +1 ng/mL/year in PTX3, *P=0.039).
This study is the first to focus on the annual change of pentraxins in a hemodialysis cohort.
American Psychological Association (APA)
Nagai, Kei& Ueda, Atsushi& Saito, Chie& Zempo-Miyaki, Asako& Yamagata, Kunihiro. 2014. Annual Decline in Pentraxin 3 Is a Risk of Vascular Access Troubles in Hemodialysis Patients. International Journal of Nephrology،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1036750
Modern Language Association (MLA)
Nagai, Kei…[et al.]. Annual Decline in Pentraxin 3 Is a Risk of Vascular Access Troubles in Hemodialysis Patients. International Journal of Nephrology No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1036750
American Medical Association (AMA)
Nagai, Kei& Ueda, Atsushi& Saito, Chie& Zempo-Miyaki, Asako& Yamagata, Kunihiro. Annual Decline in Pentraxin 3 Is a Risk of Vascular Access Troubles in Hemodialysis Patients. International Journal of Nephrology. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1036750
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1036750