Scattered and Fluorescent Photon Track Reconstruction in a Biological Tissue
Joint Authors
Kalyagina, Nina
Savelieva, Tatiana
Blondel, Walter
Loschenov, Victor
Kholodtsova, Maria N.
Grachev, Pavel V.
Source
International Journal of Photoenergy
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-25
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Appropriate analysis of biological tissue deep regions is important for tumor targeting.
This paper is concentrated on photons’ paths analysis in such biotissue as brain, because optical probing depth of fluorescent and excitation radiation differs.
A method for photon track reconstruction was developed.
Images were captured focusing on the transparent wall close and parallel to the source fibres, placed in brain tissue phantoms.
The images were processed to reconstruct the photons most probable paths between two fibres.
Results were compared with Monte Carlo simulations and diffusion approximation of the radiative transfer equation.
It was shown that the excitation radiation optical probing depth is twice more than for the fluorescent photons.
The way of fluorescent radiation spreading was discussed.
Because of fluorescent and excitation radiation spreads in different ways, and the effective anisotropy factor, geff, was proposed for fluorescent radiation.
For the brain tissue phantoms it were found to be 0.62±0.05 and 0.66±0.05 for the irradiation wavelengths 532 nm and 632.8 nm, respectively.
These calculations give more accurate information about the tumor location in biotissue.
Reconstruction of photon paths allows fluorescent and excitation probing depths determination.
The geff can be used as simplified parameter for calculations of fluorescence probing depth.
American Psychological Association (APA)
Kholodtsova, Maria N.& Grachev, Pavel V.& Savelieva, Tatiana& Kalyagina, Nina& Blondel, Walter& Loschenov, Victor. 2014. Scattered and Fluorescent Photon Track Reconstruction in a Biological Tissue. International Journal of Photoenergy،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1036988
Modern Language Association (MLA)
Kholodtsova, Maria N.…[et al.]. Scattered and Fluorescent Photon Track Reconstruction in a Biological Tissue. International Journal of Photoenergy No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1036988
American Medical Association (AMA)
Kholodtsova, Maria N.& Grachev, Pavel V.& Savelieva, Tatiana& Kalyagina, Nina& Blondel, Walter& Loschenov, Victor. Scattered and Fluorescent Photon Track Reconstruction in a Biological Tissue. International Journal of Photoenergy. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1036988
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1036988