Interleukin-8 level in pregnant women with toxoplasmosis in Kirkuk city
Other Title(s)
علاقة أنترلوكين-8 مع داء المقوسات في النساء الحوامل
Joint Authors
Rezaig, Zaynab Sulayman
Mahmud, Ahlam Ahmad
Source
Kirkuk University Journal-Scientific Studies
Issue
Vol. 14, Issue 3 (30 Sep. 2019), pp.56-67, 12 p.
Publisher
Kirkuk University College of Science
Publication Date
2019-09-30
Country of Publication
Iraq
No. of Pages
12
Main Subjects
Topics
Abstract EN
A cross sectional study was carried out in Kirkuk city from 15th of June 2018 to 15th of December 2018.
The study included 100 pregnant women and 50 healthy individuals.
Their ages ranged between 17-45 years old who were admitted to Kirkuk general hospital.
.
Molecular tests for real-time PCR and serological testing for detection specific Toxoplasma gondii IgM and IgG and Interleukin-8 level by using ELISA technique was done for patients and control.
The study showed that the highest rate of anti T.
gondii IgM+ IgG- antibodies (10% ) was recorded among pregnant women compared with 8% in the control group, while 22% of pregnant women were IgM+IgG+ compared 6.5% of the healthy control group.
The study revealed that 40.91% of pregnant women with positive ELISA was positive by PCR compared with 0% of patients with negative ELISA results.
The study showed that the highest rate of T.
gondii infection (diagnosed by PCR) were recorded among pregnant women at age group 27-36 year (22.55% ) and the lowest rate was within the age group 17-26 year.
The highest mean level of IL-8 recorded PCR +ve groups, in pregnant women (79.2 ±53.2 ng/ml) compared with PCR –ve groups.
There was a highly significant differences of IL-8 between pregnant women and the control group.
The study showed that the highest mean level of IL-8 (77.61±60.4 ng/ml), in pregnant at 2nd trimester of pregnancy, followed by 3rd trimester.
This study was concluded that a highly elevation of IL-8 level was correlated Toxoplasma infection in pregnant women and real time PCR is golden method in diagnosis of toxoplasmosis.
American Psychological Association (APA)
Mahmud, Ahlam Ahmad& Rezaig, Zaynab Sulayman. 2019. Interleukin-8 level in pregnant women with toxoplasmosis in Kirkuk city. Kirkuk University Journal-Scientific Studies،Vol. 14, no. 3, pp.56-67.
https://search.emarefa.net/detail/BIM-1037441
Modern Language Association (MLA)
Mahmud, Ahlam Ahmad& Rezaig, Zaynab Sulayman. Interleukin-8 level in pregnant women with toxoplasmosis in Kirkuk city. Kirkuk University Journal-Scientific Studies Vol. 14, no. 3 (Sep. 2019), pp.56-67.
https://search.emarefa.net/detail/BIM-1037441
American Medical Association (AMA)
Mahmud, Ahlam Ahmad& Rezaig, Zaynab Sulayman. Interleukin-8 level in pregnant women with toxoplasmosis in Kirkuk city. Kirkuk University Journal-Scientific Studies. 2019. Vol. 14, no. 3, pp.56-67.
https://search.emarefa.net/detail/BIM-1037441
Data Type
Journal Articles
Language
English
Notes
-
Record ID
BIM-1037441