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Safety and Efficiency of Biomimetic NanohydroxyapatitePolyamide 66 Composite in Rabbits and Primary Use in Anterior Cervical Discectomy and Fusion
Joint Authors
Zhang, Xuesong
Wang, Yan
Xu, Hui
Su, Xiaojing
Zhang, Xuelian
Source
International Journal of Polymer Science
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-04
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
This study was conducted to validate the safety and efficiency of biomimetic nanohydroxyapatite/polyamide 66 (n-HA/PA66) composite in animal model (rabbit) and report its application in anterior cervical discectomy and fusion (ACDF) for 4, 12, and 24 weeks.
N-HA/PA66 composite was implanted into one-side hind femur defects and the control defects were kept empty as blank controls.
A combination of macroscopic and histomorphometric studies was performed up to 24 weeks postoperatively and compared with normal healing.
60 cervical spondylosis myelopathy and radiculopathy patients who were subjected to ACDF using n-HA/PA66 and PEEK cage were involved in this study with six-month minimum follow-up.
Their radiographic (cage subsidence, fusion status, and segmental sagittal alignment (SSA)) and clinical (VAS and JOA scales) data before surgery and at each follow-up were recorded and compared.
Nanohydroxyapatite/polyamide 66 composite is safe and effective in animal experiment and ACDF.
American Psychological Association (APA)
Xu, Hui& Wang, Yan& Su, Xiaojing& Zhang, Xuelian& Zhang, Xuesong. 2014. Safety and Efficiency of Biomimetic NanohydroxyapatitePolyamide 66 Composite in Rabbits and Primary Use in Anterior Cervical Discectomy and Fusion. International Journal of Polymer Science،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1037564
Modern Language Association (MLA)
Xu, Hui…[et al.]. Safety and Efficiency of Biomimetic NanohydroxyapatitePolyamide 66 Composite in Rabbits and Primary Use in Anterior Cervical Discectomy and Fusion. International Journal of Polymer Science No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1037564
American Medical Association (AMA)
Xu, Hui& Wang, Yan& Su, Xiaojing& Zhang, Xuelian& Zhang, Xuesong. Safety and Efficiency of Biomimetic NanohydroxyapatitePolyamide 66 Composite in Rabbits and Primary Use in Anterior Cervical Discectomy and Fusion. International Journal of Polymer Science. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1037564
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1037564