Permeability of Porous Poly(3-hydroxybutyrate) Barriers of Single and Bilayer Type for Implant Applications
Joint Authors
Bergstrand, Anna
Uppström, Sanna
Larsson, Anette
Source
International Journal of Polymer Science
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-15
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Poly(3-hydroxybutyrate) (PHB) is a polyester which shows excellent biocompatibility and a PHB material is therefore considered suitable for many biomedical applications.
A highly porous PHB material may be designed to facilitate the transport of small molecules and body fluids or serve as a biocompatible temporary barrier.
In this study, PHB films with varying degree of porosity and pore interconnectivity were made by solvent casting using water-in-oil emulsion templates of varying composition.
The morphology was characterized by SEM and the water permeability of the films was determined.
The results show that an increased water content of the template emulsion resulted in a film with increased porosity.
A fine tuning of the film morphology of the casted films was achieved by varying the salt content of the water phase of the template emulsion.
The porosity of these films was roughly the same but the water permeability varied between 2 3 · 10 - 13 and 1486 · 10 - 13 m 2 / s .
It was concluded that the major determinant of the water permeability through these films is the pore interconnectivity.
Furthermore, we report on the formation and water permeability of bilayer PHB films consisting of a porous layer combined with a dense backing layer.
American Psychological Association (APA)
Bergstrand, Anna& Uppström, Sanna& Larsson, Anette. 2014. Permeability of Porous Poly(3-hydroxybutyrate) Barriers of Single and Bilayer Type for Implant Applications. International Journal of Polymer Science،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1037592
Modern Language Association (MLA)
Bergstrand, Anna…[et al.]. Permeability of Porous Poly(3-hydroxybutyrate) Barriers of Single and Bilayer Type for Implant Applications. International Journal of Polymer Science No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1037592
American Medical Association (AMA)
Bergstrand, Anna& Uppström, Sanna& Larsson, Anette. Permeability of Porous Poly(3-hydroxybutyrate) Barriers of Single and Bilayer Type for Implant Applications. International Journal of Polymer Science. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1037592
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1037592