Are There Clinical Differences in Limited Systemic Sclerosis according to Extension of Skin Involvement?
Joint Authors
Soriano, Enrique R.
Scolnik, Marina
Lancioni, Eliana
Sabelli, Mirtha R.
Saucedo, Carla M.
Marin, Josefina
Catoggio, Luis J.
Source
International Journal of Rheumatology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-10
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objectives.
To examine the characteristics of our patients with limited systemic sclerosis (lSSc) for differences between Barnett Type 1 (sclerodactyly only) and Type 2 or intermediate (acrosclerosis-distal but may reach up to elbows and/or knees plus face) subsets.
Methods.
Records of patients between January 1, 2000, and December 31, 2011, with SSc or those with anti-Scl-70, anticentromere, or antinucleolar antibodies were reviewed.
Only cases fulfilling ACR 1980 criteria were included and classified as diffuse or limited according to LeRoy’s criteria.
Limited SSc was separated into sclerodactyly and acrosclerosis (Barnett’s Types 1 and 2).
Results.
234 SSc patients (216 females) fulfilled criteria.
Female/male ratio was 12 : 1; 24% had dSSc and 76% lSSC (64% Type 1 and 12% Type 2).
Total follow-up was 688 patient-years.
Within lSSC, the Type 2 group had significantly shorter duration of Raynaud’s and more anti-Scl-70 and less anticentromere antibodies.
In particular, interstitial lung disease (ILD) was significantly more prevalent in Type 2 group and similar to Type 3.
Conclusions.
These results appear to confirm that extension of skin involvement within limited SSc may identify two different subsets with clinical and serologic characteristics.
American Psychological Association (APA)
Scolnik, Marina& Catoggio, Luis J.& Lancioni, Eliana& Sabelli, Mirtha R.& Saucedo, Carla M.& Marin, Josefina…[et al.]. 2014. Are There Clinical Differences in Limited Systemic Sclerosis according to Extension of Skin Involvement?. International Journal of Rheumatology،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1037604
Modern Language Association (MLA)
Scolnik, Marina…[et al.]. Are There Clinical Differences in Limited Systemic Sclerosis according to Extension of Skin Involvement?. International Journal of Rheumatology No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1037604
American Medical Association (AMA)
Scolnik, Marina& Catoggio, Luis J.& Lancioni, Eliana& Sabelli, Mirtha R.& Saucedo, Carla M.& Marin, Josefina…[et al.]. Are There Clinical Differences in Limited Systemic Sclerosis according to Extension of Skin Involvement?. International Journal of Rheumatology. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1037604
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1037604