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Non-albicans Candida Infection: An Emerging Threat
Joint Authors
Mathew, Stephen
Saini, Santosh
Deorukhkar, Sachin C.
Source
Interdisciplinary Perspectives on Infectious Diseases
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-10-22
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The very nature of infectious diseases has undergone profound changes in the past few decades.
Fungi once considered as nonpathogenic or less virulent are now recognized as a primary cause of morbidity and mortality in immunocompromised and severely ill patients.
Candida spp.
are among the most common fungal pathogens.
Candida albicans was the predominant cause of candidiasis.
However, a shift toward non-albicans Candida species has been recently observed.
These non-albicans Candida species demonstrate reduced susceptibility to commonly used antifungal drugs.
In the present study, we investigated the prevalence of non-albicans Candida spp.
among Candida isolates from various clinical specimens and analysed their virulence factors and antifungal susceptibility profile.
A total of 523 Candida spp.
were isolated from various clinical specimens.
Non-albicans Candida species were the predominant pathogens isolated.
Non-albicans Candida species also demonstrated the production of virulence factors once attributed to Candida albicans.
Non-albicans Candida demonstrated high resistance to azole group of antifungal agents.
Therefore, it can be concluded that non-albicans Candida species have emerged as an important cause of infections.
Their isolation from clinical specimen can no longer be ignored as a nonpathogenic isolate nor can it be dismissed as a contaminant.
American Psychological Association (APA)
Deorukhkar, Sachin C.& Saini, Santosh& Mathew, Stephen. 2014. Non-albicans Candida Infection: An Emerging Threat. Interdisciplinary Perspectives on Infectious Diseases،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1037712
Modern Language Association (MLA)
Deorukhkar, Sachin C.…[et al.]. Non-albicans Candida Infection: An Emerging Threat. Interdisciplinary Perspectives on Infectious Diseases No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1037712
American Medical Association (AMA)
Deorukhkar, Sachin C.& Saini, Santosh& Mathew, Stephen. Non-albicans Candida Infection: An Emerging Threat. Interdisciplinary Perspectives on Infectious Diseases. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1037712
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1037712