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Seroprevalence and Seroconversion of Dengue and Implications for Clinical Diagnosis in Amazonian Children
Joint Authors
Martins, Antonio Camargo
Pereira, Thasciany Moraes
Oliart-Guzmán, Humberto
Delfino, Breno Matos
Mantovani, Saulo Augusto Silva
Braña, Athos Muniz
Branco, Fernando Luiz Cunha Castelo
Filgueira Júnior, José Alcântara
Santos, Ana Paula
Ramalho, Alanderson Alves
Guimarães, Andréia Silva
de Araújo, Thiago Santos
Oliveira, Cristieli Sérgio de Menezes
da Fonseca, Benedito Antônio Lopes
da Silva-Nunes, M.
Source
Interdisciplinary Perspectives on Infectious Diseases
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-12-07
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
This study aimed to evaluate the prevalence of serum IgG dengue in children in an Amazonian population, to assess the seroconversion rate in 12 months, and to estimate how many seropositive children had a prior clinical diagnosis of dengue.
We conducted a population-based study between 2010 and 2011, with children aged 6 months to 12 years that were living in the urban area of a small town in the Brazilian Amazon.
The prevalence of IgG antibodies against dengue antigens was determined by indirect ELISA technique, and seronegative children were reexamined after 12 months to determine seroconversion rates.
Results showed seroprevalence of IgG antibodies against dengue type of 2.9%, with no significant association between age, race, and sex.
In seropositive children, only 8.4% had received a clinical diagnosis of dengue, and the ratio of clinically diagnosed cases and subclinical cases was 1 : 11.
The seroconversion rate between 2010 and 2011 was 1.4% (CI 3.8% to 35.1%).
The seroprevalence of dengue in this pediatric population was low, and the vast majority of cases were not clinically detected, suggesting a difficulty in making the clinical diagnosis in children and a high frequency of asymptomatic infections.
American Psychological Association (APA)
Martins, Antonio Camargo& Pereira, Thasciany Moraes& Oliart-Guzmán, Humberto& Delfino, Breno Matos& Mantovani, Saulo Augusto Silva& Braña, Athos Muniz…[et al.]. 2014. Seroprevalence and Seroconversion of Dengue and Implications for Clinical Diagnosis in Amazonian Children. Interdisciplinary Perspectives on Infectious Diseases،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1037714
Modern Language Association (MLA)
Martins, Antonio Camargo…[et al.]. Seroprevalence and Seroconversion of Dengue and Implications for Clinical Diagnosis in Amazonian Children. Interdisciplinary Perspectives on Infectious Diseases No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1037714
American Medical Association (AMA)
Martins, Antonio Camargo& Pereira, Thasciany Moraes& Oliart-Guzmán, Humberto& Delfino, Breno Matos& Mantovani, Saulo Augusto Silva& Braña, Athos Muniz…[et al.]. Seroprevalence and Seroconversion of Dengue and Implications for Clinical Diagnosis in Amazonian Children. Interdisciplinary Perspectives on Infectious Diseases. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1037714
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1037714