Simultaneous Determination of Uric Acid and Xanthine Using a Poly(Methylene Blue) and Electrochemically Reduced Graphene Oxide Composite Film Modified Electrode
Joint Authors
Liu, Gen
Ma, Wei
Luo, Yan
Sun, Deng-ming
Shao, Shuang
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-11
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Poly(methylene blue) and electrochemically reduced graphene oxide composite film modified electrode (PMB-ERGO/GCE) was successfully fabricated by electropolymerization and was used for simultaneous determination of uric acid (UA) and xanthine (Xa).
Based on the excellent electrocatalytic activity of PMB-ERGO/GCE, the electrochemical behaviors of UA and Xa were studied by cyclic voltammetry (CV) and square wave voltammetry (SWV).
Two anodic sensitive peaks at 0.630 V (versus Ag/AgCl) for UA and 1.006 V (versus Ag/AgCl) for Xa were given by CV in pH 3.0 phosphate buffer.
The calibration curves for UA and Xa were obtained in the range of 8.00 × 10−8~4.00 × 10−4 M and 1.00 × 10−7~4.00 × 10−4 M, respectively, by SWV.
The detection limits for UA and Xa were 3 .
00 × 10 - 8 M and 5.00 × 10 - 8 M, respectively.
Finally, the proposed method was applied to simultaneously determine UA and Xa in human urine with good selectivity and high sensitivity.
American Psychological Association (APA)
Liu, Gen& Ma, Wei& Luo, Yan& Sun, Deng-ming& Shao, Shuang. 2014. Simultaneous Determination of Uric Acid and Xanthine Using a Poly(Methylene Blue) and Electrochemically Reduced Graphene Oxide Composite Film Modified Electrode. Journal of Analytical Methods in Chemistry،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1039844
Modern Language Association (MLA)
Liu, Gen…[et al.]. Simultaneous Determination of Uric Acid and Xanthine Using a Poly(Methylene Blue) and Electrochemically Reduced Graphene Oxide Composite Film Modified Electrode. Journal of Analytical Methods in Chemistry No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-1039844
American Medical Association (AMA)
Liu, Gen& Ma, Wei& Luo, Yan& Sun, Deng-ming& Shao, Shuang. Simultaneous Determination of Uric Acid and Xanthine Using a Poly(Methylene Blue) and Electrochemically Reduced Graphene Oxide Composite Film Modified Electrode. Journal of Analytical Methods in Chemistry. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1039844
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1039844