New Bioactive Oleanane Type Compounds from Coriandrum sativum Linn.
Joint Authors
Iqbal, Muhammad
Bilal, Muhammad
Iqbal, Rubina
Akram, Muhammad
Bakhsh Baloch, Imam
Baloch, Musa Kaleem
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-18
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Five (1–5) new bioactive oleanane type triterpenoids have been isolated from ethyl acetate soluble fraction of ethanolic extract of Coriandrum sativum Linn.
of Umbelliferae family.
Ethanolic extract of the whole plant was fractionated in organic solvents.
Ethyl acetate fraction was subjected to column chromatography on HPLC RP-18 to get 1-oxo-11β,21β-dihydroxy-oleanane (1), 1-oxo-11β-hydroxy-21β-O-acetyloleanane (2), 1-oxo-11β-hydroxy-21β-O-angeloyloleanane (3), 1-oxo-11β-O-angeloyl-21β-O-acetyloleanane (4), and 1-oxo-11β,21β-O-dibenzoyloleanane (5).
The structures were elucidated after analysis of spectroscopic data, UV, IR, NMR (1H, 13C, 1D, and 2D), and mass measurements.
Suspension in water of crude ethyl acetate extract was employed to treat sheep with ringworm disease.
All isolated compounds (1–5) displayed excellent activity in terms of inhibition zones, MICs, MBCs, and MFCs against both bacteria and fungi.
Ethyl acetate extract showed excellent antiringworm activity in sheep.
American Psychological Association (APA)
Iqbal, Muhammad& Bilal, Muhammad& Iqbal, Rubina& Akram, Muhammad& Bakhsh Baloch, Imam& Baloch, Musa Kaleem. 2014. New Bioactive Oleanane Type Compounds from Coriandrum sativum Linn.. Journal of Chemistry،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1039975
Modern Language Association (MLA)
Iqbal, Muhammad…[et al.]. New Bioactive Oleanane Type Compounds from Coriandrum sativum Linn.. Journal of Chemistry No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1039975
American Medical Association (AMA)
Iqbal, Muhammad& Bilal, Muhammad& Iqbal, Rubina& Akram, Muhammad& Bakhsh Baloch, Imam& Baloch, Musa Kaleem. New Bioactive Oleanane Type Compounds from Coriandrum sativum Linn.. Journal of Chemistry. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1039975
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1039975