In Silico Study of Leishmania donovani α-β Tubulin and Inhibitors
Joint Authors
Ramalho, Teodorico C.
Assis, Tamiris M.
Mancini, Daiana T.
da Cunha, Elaine F. F.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-01
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Leishmania donovani is a parasite that causes visceral leishmaniasis, a severe form of leishmaniasis that affects vital organs.
An important target for the treatment of this disease is the protein α-β tubulin, which was modeled in this paper and proposed as a target for the treatment of visceral leishmaniasis.
Two classes of compounds were studied, dinitroanilines and oxadiazoles.
According to the docking results, dinitroanilines interact better with the L loop domain and oxadiazoles interact better with the colchicine domain.
American Psychological Association (APA)
Assis, Tamiris M.& Mancini, Daiana T.& Ramalho, Teodorico C.& da Cunha, Elaine F. F.. 2014. In Silico Study of Leishmania donovani α-β Tubulin and Inhibitors. Journal of Chemistry،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1040001
Modern Language Association (MLA)
Assis, Tamiris M.…[et al.]. In Silico Study of Leishmania donovani α-β Tubulin and Inhibitors. Journal of Chemistry No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1040001
American Medical Association (AMA)
Assis, Tamiris M.& Mancini, Daiana T.& Ramalho, Teodorico C.& da Cunha, Elaine F. F.. In Silico Study of Leishmania donovani α-β Tubulin and Inhibitors. Journal of Chemistry. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1040001
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1040001
