Nonhuman Primate Models of Type 1 Diabetes Mellitus for Islet Transplantation
Joint Authors
Zhu, Haitao
Yu, Liang
He, Yayi
Wang, Bo
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-10-20
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Islet transplantation is an attractive treatment of type 1 diabetes mellitus (T1DM).
Animal models of diabetes mellitus (DM) contribute a lot to the experimental studies of islet transplantation and to evaluations of isolated islet grafts for future clinical applications.
Diabetic nonhuman primates (NHPs) represent the suitable models of DMs to better evaluate the effectiveness of islet transplantation, to assess new strategies for controlling blood glucose (BG), relieving immune rejection, or prolonging islet survival, and eventually to translate the preclinical data into tangible clinical practice.
This review introduces some NHP models of DM, clarifies why and how the models should be used, and elucidates the usefulness and limitations of the models in islet transplantation.
American Psychological Association (APA)
Zhu, Haitao& Yu, Liang& He, Yayi& Wang, Bo. 2014. Nonhuman Primate Models of Type 1 Diabetes Mellitus for Islet Transplantation. Journal of Diabetes Research،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1040368
Modern Language Association (MLA)
Zhu, Haitao…[et al.]. Nonhuman Primate Models of Type 1 Diabetes Mellitus for Islet Transplantation. Journal of Diabetes Research No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1040368
American Medical Association (AMA)
Zhu, Haitao& Yu, Liang& He, Yayi& Wang, Bo. Nonhuman Primate Models of Type 1 Diabetes Mellitus for Islet Transplantation. Journal of Diabetes Research. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1040368
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1040368