Comparative Analysis of Changes of Myocardial Angiogenesis and Energy Metabolism in Postinfarction and Diabetic Damage of Rat Heart
Joint Authors
Afanasiev, Sergey A.
Egorova, Margarita V.
Kondratyeva, Dina S.
Batalov, Roman E.
Popov, Sergey V.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-12
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Comparative study of changes in myocardial activity of lactate dehydrogenase (LDH), succinate dehydrogenase (SDH), and capillary density distribution in the experimental models of diabetic and postinfarction damage of rat heart was performed.
Data showed that decrease in LDH and SDH activities was observed in both pathologies which can suggest abnormal processes of glycolysis and oxidative phosphorylation in cardiac mitochondria.
Activity of LDH and SDH in combined pathologies was comparative with the corresponding values of these parameters in control group.
The authors hypothesize that these differences can be caused by specifics of myocardial vascularization.
The results of the study showed that an increase in capillary density was found in all groups of rats with pathologies compared with control group.
However, no significant differences in the intensity of angiogenesis processes were found between groups with pathologies.
American Psychological Association (APA)
Afanasiev, Sergey A.& Egorova, Margarita V.& Kondratyeva, Dina S.& Batalov, Roman E.& Popov, Sergey V.. 2014. Comparative Analysis of Changes of Myocardial Angiogenesis and Energy Metabolism in Postinfarction and Diabetic Damage of Rat Heart. Journal of Diabetes Research،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1040381
Modern Language Association (MLA)
Afanasiev, Sergey A.…[et al.]. Comparative Analysis of Changes of Myocardial Angiogenesis and Energy Metabolism in Postinfarction and Diabetic Damage of Rat Heart. Journal of Diabetes Research No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-1040381
American Medical Association (AMA)
Afanasiev, Sergey A.& Egorova, Margarita V.& Kondratyeva, Dina S.& Batalov, Roman E.& Popov, Sergey V.. Comparative Analysis of Changes of Myocardial Angiogenesis and Energy Metabolism in Postinfarction and Diabetic Damage of Rat Heart. Journal of Diabetes Research. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1040381
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1040381