The Roles of Regulatory B Cells in Cancer

Joint Authors

Duan, Lihua
Shi, Guixiu
He, Yan
Qian, Hongyan
Liu, Yuan
Li, Yan

Source

Journal of Immunology Research

Issue

Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2014-06-02

Country of Publication

Egypt

No. of Pages

7

Main Subjects

Biology

Abstract EN

Regulatory B cells (Bregs), a newly described subset of B cells, have been proved to play a suppressive role in immune system.

Bregs can inhibit other immune cells through cytokines secretion and antigen presentation, which give them the role in the pathogenesis of autoimmune diseases and cancers.

There are no clear criteria to identify Bregs; different markers were used in the different experimental conditions.

Massive researches had described the functions of immune cells such as regulatory T cells (Tregs), dendritic cells (DCs), and B cells in the autoimmune disorder diseases and cancers.

More and more researches focused on the roles of Bregs and the cytokines such as Interleukin-10 (IL-10) and transforming growth factor beta (TGF-β) secreted by Bregs.

The aim of this review is to summarize the characteristics of Bregs and the roles of Bregs in cancer.

American Psychological Association (APA)

He, Yan& Qian, Hongyan& Liu, Yuan& Duan, Lihua& Li, Yan& Shi, Guixiu. 2014. The Roles of Regulatory B Cells in Cancer. Journal of Immunology Research،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1040792

Modern Language Association (MLA)

He, Yan…[et al.]. The Roles of Regulatory B Cells in Cancer. Journal of Immunology Research No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1040792

American Medical Association (AMA)

He, Yan& Qian, Hongyan& Liu, Yuan& Duan, Lihua& Li, Yan& Shi, Guixiu. The Roles of Regulatory B Cells in Cancer. Journal of Immunology Research. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1040792

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1040792