Congenital Defects in Neutrophil Dynamics
Joint Authors
Keszei, Marton
Westerberg, Lisa S.
Source
Journal of Immunology Research
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-05
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Neutrophil granulocytes are key effector cells of the vertebrate immune system.
They represent 50–70% of the leukocytes in the human blood and their loss by disease or drug side effect causes devastating bacterial infections.
Their high turnover rate, their fine-tuned killing machinery, and their arsenal of toxic vesicles leave them particularly vulnerable to various genetic deficiencies.
The aim of this review is to highlight those congenital immunodeficiencies which impede the dynamics of neutrophils, such as migration, cytoskeletal rearrangements, vesicular trafficking, and secretion.
American Psychological Association (APA)
Keszei, Marton& Westerberg, Lisa S.. 2014. Congenital Defects in Neutrophil Dynamics. Journal of Immunology Research،Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-1040831
Modern Language Association (MLA)
Keszei, Marton& Westerberg, Lisa S.. Congenital Defects in Neutrophil Dynamics. Journal of Immunology Research No. 2014 (2014), pp.1-15.
https://search.emarefa.net/detail/BIM-1040831
American Medical Association (AMA)
Keszei, Marton& Westerberg, Lisa S.. Congenital Defects in Neutrophil Dynamics. Journal of Immunology Research. 2014. Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-1040831
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1040831