Immunological Aspects of Acute and Recurrent Herpes Simplex Keratitis
Joint Authors
Source
Journal of Immunology Research
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-07
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Herpes simplex keratitis (HSK) belongs to the major causes of visual morbidity worldwide and available methods of treatment remain unsatisfactory.
Primary infection occurs usually early in life and is often asymptomatic.
Chronic visual impairment and visual loss are caused by corneal scaring, thinning, and vascularization connected with recurrent HSV infections.
The pathogenesis of herpetic keratitis is complex and is still not fully understood.
According to the current knowledge, corneal scarring and vascularization are the result of chronic inflammatory reaction against HSV antigens.
In this review we discuss the role of innate and adaptive immunities in acute and recurrent HSV ocular infection and present the potential future targets for novel therapeutical options based on immune interventions.
American Psychological Association (APA)
Rolinski, Jacek& Hus, Iwona. 2014. Immunological Aspects of Acute and Recurrent Herpes Simplex Keratitis. Journal of Immunology Research،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1040882
Modern Language Association (MLA)
Rolinski, Jacek& Hus, Iwona. Immunological Aspects of Acute and Recurrent Herpes Simplex Keratitis. Journal of Immunology Research No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1040882
American Medical Association (AMA)
Rolinski, Jacek& Hus, Iwona. Immunological Aspects of Acute and Recurrent Herpes Simplex Keratitis. Journal of Immunology Research. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1040882
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1040882