Anti-VEGF for the Management of Diabetic Macular Edema
Joint Authors
Falabella, Paulo
Stefanini, Francisco Rosa
Badaró, Emmerson
Koss, Michael
Farah, Michel Eid
Maia, Maurício
Source
Journal of Immunology Research
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-05
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Diabetic retinopathy (DR) is an important cause of vision loss around the world, being the leading cause in the population between 20 and 60 years old.
Among patients with DR, diabetic macular edema (DME) is the most frequent cause of vision impairment and represents a significant public health issue.
Macular photocoagulation has been the standard treatment for this condition reducing the risk of moderate visual loss by approximately 50%.
The role of vascular endothelial growth factor (VEGF) in DR and DME pathogenesis has been demonstrated in recent studies.
This review addresses and summarizes data from the clinical trials that investigated anti-VEGF for the management of DME and evaluates their impact on clinical practice.
The literature searches were conducted between August and October 2013 in PubMed and Cochrane Library with no date restrictions and went through the most relevant studies on pegaptanib, ranibizumab, bevacizumab, and aflibercept for the management of DME.
The efficacy and safety of intravitreal anti-VEGF as therapy for DME have recently been proved by various clinical trials providing significantly positive visual and anatomical results.
Regarding clinical practice, those outcomes have placed intravitreal injection of anti-VEGF as an option that must be considered for the treatment of DME.
American Psychological Association (APA)
Stefanini, Francisco Rosa& Badaró, Emmerson& Falabella, Paulo& Koss, Michael& Farah, Michel Eid& Maia, Maurício. 2014. Anti-VEGF for the Management of Diabetic Macular Edema. Journal of Immunology Research،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1040928
Modern Language Association (MLA)
Stefanini, Francisco Rosa…[et al.]. Anti-VEGF for the Management of Diabetic Macular Edema. Journal of Immunology Research No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1040928
American Medical Association (AMA)
Stefanini, Francisco Rosa& Badaró, Emmerson& Falabella, Paulo& Koss, Michael& Farah, Michel Eid& Maia, Maurício. Anti-VEGF for the Management of Diabetic Macular Edema. Journal of Immunology Research. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1040928
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1040928