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Unique Cytokine Signature in the Plasma of Patients with Fibromyalgia
Joint Authors
Menzies, Victoria
Sturgill, Jamie
McGee, Elizabeth
Source
Journal of Immunology Research
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-11
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Fibromyalgia (FMS) is a chronic pain syndrome with a complex but poorly understood pathogenesis affecting approximately 10 million adults in the United States.
The lack of a clear etiology of FMS has limited the effective diagnosis and treatment of this debilitating condition.
The objective of this secondary data analysis was to examine plasma cytokine levels in women with FMS using the Bio-Plex Human Cytokine 17-plex Assay.
Post hoc analysis of plasma cytokine levels was performed to evaluate patterns that were not specified a priori.
Upon examination, patients with FMS exhibited a marked reduction in T H 2 cytokines such as IL-4, IL-5, and IL-13.
The finding of this pattern of altered cytokine milieu not only supports the role of inflammation in FMS but also may lead to more definitive diagnostic tools for clinicians treating FMS.
The T H 2 suppression provides strong evidence of immune dysregulation in patients with FMS.
American Psychological Association (APA)
Sturgill, Jamie& McGee, Elizabeth& Menzies, Victoria. 2014. Unique Cytokine Signature in the Plasma of Patients with Fibromyalgia. Journal of Immunology Research،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1041016
Modern Language Association (MLA)
Sturgill, Jamie…[et al.]. Unique Cytokine Signature in the Plasma of Patients with Fibromyalgia. Journal of Immunology Research No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1041016
American Medical Association (AMA)
Sturgill, Jamie& McGee, Elizabeth& Menzies, Victoria. Unique Cytokine Signature in the Plasma of Patients with Fibromyalgia. Journal of Immunology Research. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1041016
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1041016