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Association of High Density Lipoprotein with Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratios in Coronary Artery Disease Patients
Joint Authors
Prajapati, Jayesh H.
Sahoo, Sibasis
Nikam, Tushar
Shah, Komal H.
Maheriya, Bhumika
Parmar, Meena
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-13
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
We aimed to evaluate a relationship between platelet-lymphocyte ratio (PLR) and neutrophil-lymphocyte ratio (NLR) with high density lipoprotein (HDL) cholesterol levels in coronary artery disease (CAD) patients.
Methods.
A total of 354 patients with angiographically confirmed coronary blockages were enrolled in the study.
Hematological indices and lipid profiling data of all the patients were collected.
Results.
We have observed significant association between HDL and PLR (P=0.008) and NLR (P=0.009); however no significant relationship was obtained with HDL and isolated platelet (P=0.488), neutrophil (P=0.407), and lymphocyte (P=0.952) counts in CAD patients.
The association was subjected to gender specific variation as in males PLR (P=0.024) and NLR (P=0.03) were highly elevated in low HDL patients, whereas in females the elevation could not reach the statistically significant level.
The PLR (217.47 versus 190.3; P=0.01) and NLR (6.33 versus 5.10; P=0.01) were significantly higher among the patients with acute coronary syndrome.
In young patients the PLR (P=0.007) and NLR (P=0.001) were inversely associated with HDL, whereas in older population only NLR (P=0.05) had showed a significant association.
Conclusion.
We conclude that PLR and NLR are significantly elevated in CAD patients having low HDL levels.
American Psychological Association (APA)
Prajapati, Jayesh H.& Sahoo, Sibasis& Nikam, Tushar& Shah, Komal H.& Maheriya, Bhumika& Parmar, Meena. 2014. Association of High Density Lipoprotein with Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratios in Coronary Artery Disease Patients. Journal of Lipids،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1041055
Modern Language Association (MLA)
Prajapati, Jayesh H.…[et al.]. Association of High Density Lipoprotein with Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratios in Coronary Artery Disease Patients. Journal of Lipids No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1041055
American Medical Association (AMA)
Prajapati, Jayesh H.& Sahoo, Sibasis& Nikam, Tushar& Shah, Komal H.& Maheriya, Bhumika& Parmar, Meena. Association of High Density Lipoprotein with Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratios in Coronary Artery Disease Patients. Journal of Lipids. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1041055
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1041055