In Vitro Selection of a Single-Stranded DNA Molecular Recognition Element Specific for Bromacil
Joint Authors
Williams, Ryan M.
Kulick, Amanda R.
Yedlapalli, Srilakshmi
Battistella, Louisa
Hajiran, Cyrus J.
Sooter, Letha J.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-10-22
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Bromacil is a widely used herbicide that is known to contaminate environmental systems.
Due to the hazards it presents and inefficient detection methods, it is necessary to create a rapid and efficient sensing device.
Towards this end, we have utilized a stringent in vitro selection method to identify single-stranded DNA molecular recognition elements (MRE) specific for bromacil.
We have identified one MRE with high affinity (Kd=9.6 nM) and specificity for bromacil compared to negative targets of selection and other pesticides.
The selected ssDNA MRE will be useful as the sensing element in a field-deployable bromacil detection device.
American Psychological Association (APA)
Williams, Ryan M.& Kulick, Amanda R.& Yedlapalli, Srilakshmi& Battistella, Louisa& Hajiran, Cyrus J.& Sooter, Letha J.. 2014. In Vitro Selection of a Single-Stranded DNA Molecular Recognition Element Specific for Bromacil. Journal of Nucleic Acids،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1041141
Modern Language Association (MLA)
Williams, Ryan M.…[et al.]. In Vitro Selection of a Single-Stranded DNA Molecular Recognition Element Specific for Bromacil. Journal of Nucleic Acids No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1041141
American Medical Association (AMA)
Williams, Ryan M.& Kulick, Amanda R.& Yedlapalli, Srilakshmi& Battistella, Louisa& Hajiran, Cyrus J.& Sooter, Letha J.. In Vitro Selection of a Single-Stranded DNA Molecular Recognition Element Specific for Bromacil. Journal of Nucleic Acids. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1041141
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1041141
