Effect of Nanosheet Surface Structure of Titanium Alloys on Cell Differentiation
Joint Authors
Komasa, Satoshi
Kusumoto, Tetsuji
Taguchi, Yoichiro
Nishizaki, Hiroshi
Sekino, Tohru
Umeda, Makoto
Okazaki, Joji
Kawazoe, Takayoshi
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-11-09
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Titanium alloys are the most frequently used dental implants partly because of the protective oxide coating that spontaneously forms on their surface.
We fabricated titania nanosheet (TNS) structures on titanium surfaces by NaOH treatment to improve bone differentiation on titanium alloy implants.
The cellular response to TNSs on Ti6Al4V alloy was investigated, and the ability of the modified surfaces to affect osteogenic differentiation of rat bone marrow cells and increase the success rate of titanium implants was evaluated.
The nanoscale network structures formed by alkali etching markedly enhanced the functions of cell adhesion and osteogenesis-related gene expression of rat bone marrow cells.
Other cell behaviors, such as proliferation, alkaline phosphatase activity, osteocalcin deposition, and mineralization, were also markedly increased in TNS-modified Ti6Al4V.
Our results suggest that titanium implants modified with nanostructures promote osteogenic differentiation, which may improve the biointegration of these implants into the alveolar bone.
American Psychological Association (APA)
Komasa, Satoshi& Kusumoto, Tetsuji& Taguchi, Yoichiro& Nishizaki, Hiroshi& Sekino, Tohru& Umeda, Makoto…[et al.]. 2014. Effect of Nanosheet Surface Structure of Titanium Alloys on Cell Differentiation. Journal of Nanomaterials،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1041703
Modern Language Association (MLA)
Komasa, Satoshi…[et al.]. Effect of Nanosheet Surface Structure of Titanium Alloys on Cell Differentiation. Journal of Nanomaterials No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1041703
American Medical Association (AMA)
Komasa, Satoshi& Kusumoto, Tetsuji& Taguchi, Yoichiro& Nishizaki, Hiroshi& Sekino, Tohru& Umeda, Makoto…[et al.]. Effect of Nanosheet Surface Structure of Titanium Alloys on Cell Differentiation. Journal of Nanomaterials. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1041703
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1041703