Comparison of Physicochemical Properties of Nano- and Microsized Crystals in the Urine of Calcium Oxalate Stone Patients and Control Subjects
Joint Authors
Ouyang, Jian-Ming
Gao, Jie
Wang, Feng-Xin
Xu, Meng
Gui, Bao-Song
Xue, Jun-Fa
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-30
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Purpose.
To compare the properties of different sizes of urinary crystallites between calcium oxalate (CaOx) calculi patients and healthy controls.
Methods.
We studied the average particle size, size distribution, intensity-autocorrelation curve, zeta potential (ζ), conductivity, mobility, aggregation state, and stability of different sizes of urinary crystallites by nanoparticle size analysis and transmission electron microscopy after filtration through a microporous membrane with an aperture size from 0.22 μm to 0.45, 1.2, 3, and 10 μm.
Results.
The urinary crystallites of the CaOx calculi patients were uneven and much easy to aggregate than those of controls.
The number of large-sized crystallites of the patients was significantly more than that of the controls.
The main components of the nanosized urinary crystallites in patients were CaOx monohydrate (COM), uric acid, and β-calcium phosphate, and these components were basically similar to those of the microsized urinary crystallites.
The urinary crystallites of the calculi patients were easier to aggregate than that of the controls, and the small-sized urinary crystallites were much easier to agglomerate.
Conclusions.
The urinary system of CaOx calculi patients is unstable and highly susceptible to urinary crystallite aggregation.
The rapid aggregation of urinary crystallites may be the key factor affecting urolithiasis formation.
American Psychological Association (APA)
Gao, Jie& Xue, Jun-Fa& Xu, Meng& Gui, Bao-Song& Wang, Feng-Xin& Ouyang, Jian-Ming. 2014. Comparison of Physicochemical Properties of Nano- and Microsized Crystals in the Urine of Calcium Oxalate Stone Patients and Control Subjects. Journal of Nanomaterials،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1041906
Modern Language Association (MLA)
Gao, Jie…[et al.]. Comparison of Physicochemical Properties of Nano- and Microsized Crystals in the Urine of Calcium Oxalate Stone Patients and Control Subjects. Journal of Nanomaterials No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1041906
American Medical Association (AMA)
Gao, Jie& Xue, Jun-Fa& Xu, Meng& Gui, Bao-Song& Wang, Feng-Xin& Ouyang, Jian-Ming. Comparison of Physicochemical Properties of Nano- and Microsized Crystals in the Urine of Calcium Oxalate Stone Patients and Control Subjects. Journal of Nanomaterials. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1041906
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1041906