Facile Synthesis of Curcumin-Loaded Starch-Maleate Nanoparticles
Joint Authors
Pang, Suh Cem
Chin, Suk Fun
Tay, Soon Hiang
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
We have demonstrated the loading of curcumin onto starch maleate (SM) under mild conditions by mixing dissolved curcumin and SM nanoparticles separately in absolute ethanol and ethanol/aqueous (40 : 60 v/v), respectively.
Curcumin-loaded starch-maleate (CurSM) nanoparticles were subsequently precipitated from a homogeneous mixture of these solutions in absolute ethanol based on the solvent exchange method.
TEM analysis indicated that the diameters of CurSM nanoparticles were ranged between 30 nm and 110 nm with a mean diameter of 50 nm.
The curcumin loading capacity of SM as a function of loading duration was investigated using the UV-visible spectrophotometer.
The loading of curcumin onto SM increased rapidly initially with loading duration, and the curcumin loading capacity of 15 mg/g was reached within 12 hours.
CurSM nanoparticles exhibited substantially higher water solubility of 6.0 × 10−2 mg/mL which is about 300 times higher than that of pure curcumin.
With enhanced water solubility and bioaccessibility of curcumin, the potential utility of CurSM nanoparticles in various biomedical applications is therefore envisaged.
American Psychological Association (APA)
Pang, Suh Cem& Tay, Soon Hiang& Chin, Suk Fun. 2014. Facile Synthesis of Curcumin-Loaded Starch-Maleate Nanoparticles. Journal of Nanomaterials،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1041969
Modern Language Association (MLA)
Pang, Suh Cem…[et al.]. Facile Synthesis of Curcumin-Loaded Starch-Maleate Nanoparticles. Journal of Nanomaterials No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1041969
American Medical Association (AMA)
Pang, Suh Cem& Tay, Soon Hiang& Chin, Suk Fun. Facile Synthesis of Curcumin-Loaded Starch-Maleate Nanoparticles. Journal of Nanomaterials. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1041969
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1041969