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A Review on Characterizations and Biocompatibility of Functionalized Carbon Nanotubes in Drug Delivery Design
Joint Authors
Arulselvan, Palanisamy
Tan, Julia M.
Ithnin, Hairuszah
Hussein, Mohd Zobir
Fakurazi, Sharida
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-20, 20 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-15
Country of Publication
Egypt
No. of Pages
20
Main Subjects
Abstract EN
The revolutionary development of functionalized carbon nanotubes (f-CNTs) for applications in nanomedicine has emerged as one of the most interesting fields, which has increased exponentially in recent years.
This is due to their appealing physical and chemical properties, as well as their unique architecture.
After a brief introduction on the physicochemical properties of carbon nanotubes (CNTs), we described several functionalization methods for the surface modification of CNTs, with the aim to facilitate their solubility in physiological aqueous environment.
This review focuses on recent advances in drug delivery design based on f-CNTs with an emphasis on the determination of various parameters involved and characterization methods used in order to achieve higher therapeutic efficacy of targeted drug delivery.
In particular, we will highlight a variety of different analytical techniques which can be used to characterize the elemental composition, chemical structure, and functional groups introduced onto the CNTs after surface modification.
We also review the current progress of available in vitro biocompatibility assays based on f-CNTs and then discuss their toxicological profile and biodistribution for advanced drug delivery.
American Psychological Association (APA)
Tan, Julia M.& Arulselvan, Palanisamy& Fakurazi, Sharida& Ithnin, Hairuszah& Hussein, Mohd Zobir. 2014. A Review on Characterizations and Biocompatibility of Functionalized Carbon Nanotubes in Drug Delivery Design. Journal of Nanomaterials،Vol. 2014, no. 2014, pp.1-20.
https://search.emarefa.net/detail/BIM-1042030
Modern Language Association (MLA)
Tan, Julia M.…[et al.]. A Review on Characterizations and Biocompatibility of Functionalized Carbon Nanotubes in Drug Delivery Design. Journal of Nanomaterials No. 2014 (2014), pp.1-20.
https://search.emarefa.net/detail/BIM-1042030
American Medical Association (AMA)
Tan, Julia M.& Arulselvan, Palanisamy& Fakurazi, Sharida& Ithnin, Hairuszah& Hussein, Mohd Zobir. A Review on Characterizations and Biocompatibility of Functionalized Carbon Nanotubes in Drug Delivery Design. Journal of Nanomaterials. 2014. Vol. 2014, no. 2014, pp.1-20.
https://search.emarefa.net/detail/BIM-1042030
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1042030