Low-Salt Intake during Mating or Gestation in Rats Is Associated with Low Birth and Survival Rates of Babies
Joint Authors
Chou, Ranna
Hara, Anna
Du, DongDong
Shimizu, Namiko
Sakuyama, Hiroe
Uehara, Yoshio
Source
Journal of Nutrition and Metabolism
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-14
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
We investigated the influence of maternal salt restriction during mating or gestation on birth rate and offspring growth in Dahl salt-sensitive rats (DS).
DS were divided into 5 groups: DS fed a low-salt (0.3% NaCl, w/w) (DS-low) or high-salt (4% NaCl, w/w) diet (DS-high) during mating and DS-high or DS-low during gestation, and DS fed regular chow (0.75% NaCl, w/w) (DS-regular) throughout mating and gestation.
During the unspecified periods, the rats were given regular chow.
DS-low during mating delivered fewer infants than high-salt mothers (P<0.05).
The birth rate on regular chow was 87%.
Six out of 11 DS-low rats during pregnancy produced pups while the rats fed a high-salt diet all delivered pups (P<0.025).
The pup survival rate was 67% for high-salt mothers during mating and 54% for mothers on a low-salt diet.
The pup survival rate was 95% for mothers on a high-salt diet during pregnancy and 64% for mothers on a low-salt diet (P<0.0001).
Seven out of 8 DS-regular rats during mating delivered 59 neonates.
However, 66% of the neonates survived.
A low-salt diet during mating or pregnancy lowers birth rate and the neonates from low-salt mothers during pregnancy were more likely to die than those from high-salt mothers.
American Psychological Association (APA)
Chou, Ranna& Hara, Anna& Du, DongDong& Shimizu, Namiko& Sakuyama, Hiroe& Uehara, Yoshio. 2014. Low-Salt Intake during Mating or Gestation in Rats Is Associated with Low Birth and Survival Rates of Babies. Journal of Nutrition and Metabolism،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1042155
Modern Language Association (MLA)
Chou, Ranna…[et al.]. Low-Salt Intake during Mating or Gestation in Rats Is Associated with Low Birth and Survival Rates of Babies. Journal of Nutrition and Metabolism No. 2014 (Dec. 2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1042155
American Medical Association (AMA)
Chou, Ranna& Hara, Anna& Du, DongDong& Shimizu, Namiko& Sakuyama, Hiroe& Uehara, Yoshio. Low-Salt Intake during Mating or Gestation in Rats Is Associated with Low Birth and Survival Rates of Babies. Journal of Nutrition and Metabolism. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1042155
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1042155