Evaluation of Beneficial Metabolic Effects of Berries in High-Fat Fed C57BL6J Mice
Joint Authors
Heyman, Lovisa
Axling, Ulrika
Blanco, Narda
Sterner, Olov
Holm, Cecilia
Berger, Karin
Source
Journal of Nutrition and Metabolism
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-14
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Objective.
The aim of the study was to screen eight species of berries for their ability to prevent obesity and metabolic abnormalities associated with type 2 diabetes.
Methods.
C57BL/6J mice were assigned the following diets for 13 weeks: low-fat diet, high-fat diet or high-fat diet supplemented (20%) with lingonberry, blackcurrant, bilberry, raspberry, açai, crowberry, prune or blackberry.
Results.
The groups receiving a high-fat diet supplemented with lingonberries, blackcurrants, raspberries or bilberries gained less weight and had lower fasting insulin levels than the control group receiving high-fat diet without berries.
Lingonberries, and also blackcurrants and bilberries, significantly decreased body fat content, hepatic lipid accumulation, and plasma levels of the inflammatory marker PAI-1, as well as mediated positive effects on glucose homeostasis.
The group receiving açai displayed increased weight gain and developed large, steatotic livers.
Quercetin glycosides were detected in the lingonberry and the blackcurrant diets.
Conclusion.
Lingonberries were shown to fully or partially prevent the detrimental metabolic effects induced by high-fat diet.
Blackcurrants and bilberries had similar properties, but to a lower degree.
We propose that the beneficial metabolic effects of lingonberries could be useful in preventing obesity and related disorders.
American Psychological Association (APA)
Heyman, Lovisa& Axling, Ulrika& Blanco, Narda& Sterner, Olov& Holm, Cecilia& Berger, Karin. 2014. Evaluation of Beneficial Metabolic Effects of Berries in High-Fat Fed C57BL6J Mice. Journal of Nutrition and Metabolism،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1042158
Modern Language Association (MLA)
Heyman, Lovisa…[et al.]. Evaluation of Beneficial Metabolic Effects of Berries in High-Fat Fed C57BL6J Mice. Journal of Nutrition and Metabolism No. 2014 (Dec. 2014), pp.1-12.
https://search.emarefa.net/detail/BIM-1042158
American Medical Association (AMA)
Heyman, Lovisa& Axling, Ulrika& Blanco, Narda& Sterner, Olov& Holm, Cecilia& Berger, Karin. Evaluation of Beneficial Metabolic Effects of Berries in High-Fat Fed C57BL6J Mice. Journal of Nutrition and Metabolism. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1042158
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1042158