Absence of HPV Infection Is Associated with Smoker Patients with Squamous Cell Carcinoma of the Oropharynx
Joint Authors
Soares, Gláucia Resende
Demathé, Adriana
Mattar, Neivio José
Biasoli, Éder Ricardo
Miyahara, Glauco Issamu
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-30
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The purpose of this study was to evaluate the survival of patients with SCC of the oropharynx, according to the presence of HPV and tobacco consumption.
A total of 37 patients were followed up for at least 5 years after being diagnosed with SCC of the oropharynx.
The biopsy tissue was submitted to the polymerase chain reaction (PCR) and in situ hybridization (ISH) methods for broad determination of HPV presence, to identify the presence of high-risk viruses (16 and 18).
12 of the 37 (32.4%) samples were HPV positive, whereas the two specific types of virus were identified in two samples for HPV-16 and in no samples for HPV-18.
We observed no significant effect of the virus in survival analysis, irrespective of tobacco consumption.
The level of tobacco consumption was significantly higher in the group of HPV-negative patients ( P = 0.0283 ), in which all the patients in this group were smokers.
Therefore, HPV did not change the survival of patients with SCC of the oropharynx in this study, indicating that factors other than tobacco need to be studied in conjunction with it, and the level of tobacco consumption is significantly higher in the group of HPV-negative patients.
American Psychological Association (APA)
Soares, Gláucia Resende& Demathé, Adriana& Mattar, Neivio José& Biasoli, Éder Ricardo& Miyahara, Glauco Issamu. 2014. Absence of HPV Infection Is Associated with Smoker Patients with Squamous Cell Carcinoma of the Oropharynx. Journal of Oncology،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1042235
Modern Language Association (MLA)
Soares, Gláucia Resende…[et al.]. Absence of HPV Infection Is Associated with Smoker Patients with Squamous Cell Carcinoma of the Oropharynx. Journal of Oncology No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1042235
American Medical Association (AMA)
Soares, Gláucia Resende& Demathé, Adriana& Mattar, Neivio José& Biasoli, Éder Ricardo& Miyahara, Glauco Issamu. Absence of HPV Infection Is Associated with Smoker Patients with Squamous Cell Carcinoma of the Oropharynx. Journal of Oncology. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1042235
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1042235