Comparison of Short and Continuous Hydration Regimen in Chemotherapy Containing Intermediate- to High-Dose Cisplatin
Joint Authors
Ouchi, Akira
Asano, Masahiko
Aono, Keiya
Watanabe, Tetsuya
Kato, Takehiro
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-24
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Aim.
The efficacy of the short hydration regimen was reported in chemotherapy containing intermediate- to high-dose cisplatin, and the use of outpatient chemotherapy containing cisplatin with short hydration has been widespread in recent years.
Methods.
We compared patients with gastric cancer, lung cancer, and urothelial cancer who received outpatient chemotherapy containing cisplatin (≥60 mg/m2/cycle) with the short hydration regimen since April 2012 ( n = 13 ) with those who received hospital chemotherapy with continuous hydration between April 2011 and March 2013 ( n = 17 ) in our hospital.
Results.
Grade 2 or higher acute kidney injury occurred in 2 patients in the continuous hydration group and in no patient in the short hydration group; 1 patient discontinued treatment on account of nephrotoxicity.
There was no difference between the 2 groups in maximum creatinine increment and maximum clearance decrement.
Relative dose intensity in the short hydration group was higher than that in the continuous hydration group (89.5% versus 80.3%; P < 0.01 ).
Conclusions.
The short hydration regimen in outpatient chemotherapy containing intermediate- to high-dose cisplatin is as safe as the continuous hydration regimen and increased the efficacy of chemotherapy.
American Psychological Association (APA)
Ouchi, Akira& Asano, Masahiko& Aono, Keiya& Watanabe, Tetsuya& Kato, Takehiro. 2014. Comparison of Short and Continuous Hydration Regimen in Chemotherapy Containing Intermediate- to High-Dose Cisplatin. Journal of Oncology،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1042281
Modern Language Association (MLA)
Ouchi, Akira…[et al.]. Comparison of Short and Continuous Hydration Regimen in Chemotherapy Containing Intermediate- to High-Dose Cisplatin. Journal of Oncology No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-1042281
American Medical Association (AMA)
Ouchi, Akira& Asano, Masahiko& Aono, Keiya& Watanabe, Tetsuya& Kato, Takehiro. Comparison of Short and Continuous Hydration Regimen in Chemotherapy Containing Intermediate- to High-Dose Cisplatin. Journal of Oncology. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1042281
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1042281