Pulse-Wave Analysis of Optic Nerve Head Circulation Is Significantly Correlated with Kidney Function in Patients with and without Chronic Kidney Disease
Joint Authors
Shiba, Tomoaki
Takahashi, Mao
Maeno, Takatoshi
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Aim.
To determine whether there is a significant correlation between the optic nerve head (ONH) circulation determined by laser speckle flowgraphy (LSFG) and kidney function.
Materials.
Seventy-one subjects were investigated.
The estimated glomerular filtration rate (GFR) and serum creatinine, cystatin C, and urinary albumin excretion were measured.
The ONH circulation was determined by an analysis of the pulse wave of LSFG, and this parameter was named blowout time (BOT).
Chronic kidney disease (CKD) was defined to be present when the estimated GFR was <60 mL/min per 1.73 m2.
Pearson’s correlation coefficients were used to determine the relationship between the BOT and the kidney function.
We also examined whether there were significant differences in all parameters in patients with and without CKD.
Results.
BOT was significantly correlated with the level of creatinine ( r = - 0 .
24 , P = 0 .
04 ), the estimated GFR ( r = 0 .
42 , P = 0 .
0003 ), cystatin C ( r = - 0 .
29 , P = 0 .
01 ), and urinary albumin excretion ( r = - 0 .
29 , P = 0 .
01 ).
The BOT level in subjects with CKD was significantly lower than that in subjects without CKD ( P = 0 .
002 ).
Conclusion.
BOT in ONH by LSFG can detect the organ damage such as kidney dysfunction, CKD.
American Psychological Association (APA)
Shiba, Tomoaki& Takahashi, Mao& Maeno, Takatoshi. 2014. Pulse-Wave Analysis of Optic Nerve Head Circulation Is Significantly Correlated with Kidney Function in Patients with and without Chronic Kidney Disease. Journal of Ophthalmology،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1042450
Modern Language Association (MLA)
Shiba, Tomoaki…[et al.]. Pulse-Wave Analysis of Optic Nerve Head Circulation Is Significantly Correlated with Kidney Function in Patients with and without Chronic Kidney Disease. Journal of Ophthalmology No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1042450
American Medical Association (AMA)
Shiba, Tomoaki& Takahashi, Mao& Maeno, Takatoshi. Pulse-Wave Analysis of Optic Nerve Head Circulation Is Significantly Correlated with Kidney Function in Patients with and without Chronic Kidney Disease. Journal of Ophthalmology. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1042450
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1042450