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The Effect of Antivascular Endothelial Growth Factor Therapy on the Development of Neovascular Glaucoma after Central Retinal Vein Occlusion: A Retrospective Analysis
Joint Authors
Ryu, Christina L.
Elfersy, Adrian
Desai, Uday
Hessburg, Thomas
Edwards, Paul
Gao, Hua
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-01
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
Ischemic central retinal vein occlusion (CRVO) eyes are at high risk of developing neovascular glaucoma (NVG).
Our purpose is to investigate the effect of anti-VEGF therapy for macular edema after CRVO on the development of neovascular glaucoma (NVG) in ischemic CRVO eyes.
Methods.
This is a retrospective case series of 44 eyes from 44 patients with CRVO treated with anti-VEGF therapy for macular edema.
The primary outcome was the development of NVG.
Results.
Of the 44 eyes, 14 eyes had ischemic CRVO, and 30 eyes had nonischemic CRVO.
Nonischemic eyes received a mean of 8.4 anti-VEGF doses, over mean follow-up of 24 months.
One nonischemic eye (3.3%) developed NVD but not NVG.
The 14 ischemic eyes received a mean of 5.6 anti-VEGF doses, with mean follow-up of 23 months.
Of these 14 ischemic eyes, two eyes (14%) developed iris neovascularization and 3 eyes (21%) developed posterior neovascularization.
Three of these 5 eyes with neovascularization progressed to NVG, at 19.7 months after symptom onset, on average.
Conclusion.
Anti-VEGF therapy for macular edema may delay, but does not prevent, the development of ocular NV in ischemic CRVO.
Significant risk of NVG still exists for ischemic CRVO eyes.
American Psychological Association (APA)
Ryu, Christina L.& Elfersy, Adrian& Desai, Uday& Hessburg, Thomas& Edwards, Paul& Gao, Hua. 2014. The Effect of Antivascular Endothelial Growth Factor Therapy on the Development of Neovascular Glaucoma after Central Retinal Vein Occlusion: A Retrospective Analysis. Journal of Ophthalmology،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1042455
Modern Language Association (MLA)
Ryu, Christina L.…[et al.]. The Effect of Antivascular Endothelial Growth Factor Therapy on the Development of Neovascular Glaucoma after Central Retinal Vein Occlusion: A Retrospective Analysis. Journal of Ophthalmology No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1042455
American Medical Association (AMA)
Ryu, Christina L.& Elfersy, Adrian& Desai, Uday& Hessburg, Thomas& Edwards, Paul& Gao, Hua. The Effect of Antivascular Endothelial Growth Factor Therapy on the Development of Neovascular Glaucoma after Central Retinal Vein Occlusion: A Retrospective Analysis. Journal of Ophthalmology. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1042455
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1042455