Genetics of Keratoconus: Where Do We Stand?

Joint Authors

Abu-Amero, Khaled K.
Al-Muammar, Abdulrahman M.
Kondkar, Altaf A.

Source

Journal of Ophthalmology

Issue

Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-11, 11 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2014-08-28

Country of Publication

Egypt

No. of Pages

11

Main Subjects

Medicine

Abstract EN

Keratoconus is a progressive thinning and anterior protrusion of the cornea that results in steepening and distortion of the cornea, altered refractive powers, and reduced vision.

Keratoconus has a complex multifactorial etiology, with environmental, behavioral, and multiple genetic components contributing to the disease pathophysiology.

Using genome-wide and candidate gene approaches several genomic loci and genes have been identified that highlight the complex molecular etiology of this disease.

The review focuses on current knowledge of these genetic risk factors associated with keratoconus.

American Psychological Association (APA)

Abu-Amero, Khaled K.& Al-Muammar, Abdulrahman M.& Kondkar, Altaf A.. 2014. Genetics of Keratoconus: Where Do We Stand?. Journal of Ophthalmology،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1042589

Modern Language Association (MLA)

Abu-Amero, Khaled K.…[et al.]. Genetics of Keratoconus: Where Do We Stand?. Journal of Ophthalmology No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1042589

American Medical Association (AMA)

Abu-Amero, Khaled K.& Al-Muammar, Abdulrahman M.& Kondkar, Altaf A.. Genetics of Keratoconus: Where Do We Stand?. Journal of Ophthalmology. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1042589

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1042589