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Alterations of Eye Movement Control in Neurodegenerative Movement Disorders
Joint Authors
Pinkhardt, Elmar H.
Gorges, Martin
Kassubek, Jan
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-18
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The evolution of the fovea centralis, the most central part of the retina and the area of the highest visual accuracy, requires humans to shift their gaze rapidly (saccades) to bring some object of interest within the visual field onto the fovea.
In addition, humans are equipped with the ability to rotate the eye ball continuously in a highly predicting manner (smooth pursuit) to hold a moving target steadily upon the retina.
The functional deficits in neurodegenerative movement disorders (e.g., Parkinsonian syndromes) involve the basal ganglia that are critical in all aspects of movement control.
Moreover, neocortical structures, the cerebellum, and the midbrain may become affected by the pathological process.
A broad spectrum of eye movement alterations may result, comprising smooth pursuit disturbance (e.g., interrupting saccades), saccadic dysfunction (e.g., hypometric saccades), and abnormal attempted fixation (e.g., pathological nystagmus and square wave jerks).
On clinical grounds, videooculography is a sensitive noninvasive in vivo technique to classify oculomotion function alterations.
Eye movements are a valuable window into the integrity of central nervous system structures and their changes in defined neurodegenerative conditions, that is, the oculomotor nuclei in the brainstem together with their directly activating supranuclear centers and the basal ganglia as well as cortical areas of higher cognitive control of attention.
American Psychological Association (APA)
Gorges, Martin& Pinkhardt, Elmar H.& Kassubek, Jan. 2014. Alterations of Eye Movement Control in Neurodegenerative Movement Disorders. Journal of Ophthalmology،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1042591
Modern Language Association (MLA)
Gorges, Martin…[et al.]. Alterations of Eye Movement Control in Neurodegenerative Movement Disorders. Journal of Ophthalmology No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1042591
American Medical Association (AMA)
Gorges, Martin& Pinkhardt, Elmar H.& Kassubek, Jan. Alterations of Eye Movement Control in Neurodegenerative Movement Disorders. Journal of Ophthalmology. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1042591
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1042591