The Effects of Intravitreal Bevacizumab in Infectious and Noninfectious Uveitic Macular Edema
Joint Authors
Gupta, Vishali
Al-Dhibi, Hassan
Hamade, Issam H.
Al-Halafi, Ali
Barry, Maan
Chacra, Charbel Bou
Tabbara, Khalid F.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-21
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background/Aims.
To assess the effect of intravitreal bevacizumab injection (IVBI) for the treatment of macular edema due to infectious and noninfectious uveitides.
Design.
Retrospective interventional case series.
Methods.
A chart review was performed on all the patients who were diagnosed with uveitic macular edema (UME) and received 1.25 mg of IVBI at two referral centers in Riyadh, Saudi Arabia.
All included patients had their visual acuity and macular thickness analyzed at baseline and at 1 and 3 months following IVBI and any sign of reactivation was noted.
Results.
The mean age of patients was 41±16 years with a mean followup of 4±1 months.
Ten patients had idiopathic intermediate uveitis, 9 patients had Behcet’s disease, 10 had idiopathic panuveitis, and twelve patients had presumed ocular tuberculosis uveitis.
Following IVBI, the mean LogMAR visual acuity improved from 0.8±0.8 at baseline to 0.4±0.5 at 1 month and 0.3±0.5 at 3 months (P<0.002, at 3 months).
The mean macular thickness was 430±132 μm at baseline.
Following IVBI macular thickness improved to 286±93 μm at 1 month and to 265±88 μm at 3 months of followup (P<0.001, at 3 months).
Conclusion.
Bevacizumab was effective in the management of UME associated with both infectious and noninfectious uveitides.
Intravitreal bevacizumab induced remission of UME with infectious uveitis and had no immunosuppressive effect against infectious agents.
American Psychological Association (APA)
Al-Dhibi, Hassan& Hamade, Issam H.& Al-Halafi, Ali& Barry, Maan& Chacra, Charbel Bou& Gupta, Vishali…[et al.]. 2014. The Effects of Intravitreal Bevacizumab in Infectious and Noninfectious Uveitic Macular Edema. Journal of Ophthalmology،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1042606
Modern Language Association (MLA)
Al-Dhibi, Hassan…[et al.]. The Effects of Intravitreal Bevacizumab in Infectious and Noninfectious Uveitic Macular Edema. Journal of Ophthalmology No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1042606
American Medical Association (AMA)
Al-Dhibi, Hassan& Hamade, Issam H.& Al-Halafi, Ali& Barry, Maan& Chacra, Charbel Bou& Gupta, Vishali…[et al.]. The Effects of Intravitreal Bevacizumab in Infectious and Noninfectious Uveitic Macular Edema. Journal of Ophthalmology. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1042606
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1042606