Do Nutritional Supplements Have a Role in Age Macular Degeneration Prevention?
Joint Authors
García-Layana, Alfredo
Gallego-Pinazo, Roberto
García-Medina, José Javier
Diaz-Llopis, Manuel
Araiz, Javier
López-Gálvez, María Isabel
Gómez-Ulla, Francisco
Casaroli-Marano, Ricardo
Manzanas, Lucía
Salas, Anna
Pinazo-Duran, Maria Dolores
Arias, L.
Zapata, Miguel A.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-23
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Purpose.
To review the proposed pathogenic mechanisms of age macular degeneration (AMD), as well as the role of antioxidants (AOX) and omega-3 fatty acids (ω-3) supplements in AMD prevention.
Materials and Methods.
Current knowledge on the cellular/molecular mechanisms of AMD and the epidemiologic/experimental studies on the effects of AOX and ω-3 were addressed all together with the scientific evidence and the personal opinion of professionals involved in the Retina Group of the OFTARED (Spain).
Results.
High dietary intakes of ω-3 and macular pigments lutein/zeaxanthin are associated with lower risk of prevalence and incidence in AMD.
The Age-Related Eye Disease study (AREDS) showed a beneficial effect of high doses of vitamins C, E, beta-carotene, and zinc/copper in reducing the rate of progression to advanced AMD in patients with intermediate AMD or with one-sided late AMD.
The AREDS-2 study has shown that lutein and zeaxanthin may substitute beta-carotene because of its potential relationship with increased lung cancer incidence.
Conclusion.
Research has proved that elder people with poor diets, especially with low AOX and ω-3 micronutrients intake and subsequently having low plasmatic levels, are more prone to developing AMD.
Micronutrient supplementation enhances antioxidant defense and healthy eyes and might prevent/retard/modify AMD.
American Psychological Association (APA)
Pinazo-Duran, Maria Dolores& Gómez-Ulla, Francisco& Arias, L.& Araiz, Javier& Casaroli-Marano, Ricardo& Gallego-Pinazo, Roberto…[et al.]. 2014. Do Nutritional Supplements Have a Role in Age Macular Degeneration Prevention?. Journal of Ophthalmology،Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-1042643
Modern Language Association (MLA)
Pinazo-Duran, Maria Dolores…[et al.]. Do Nutritional Supplements Have a Role in Age Macular Degeneration Prevention?. Journal of Ophthalmology No. 2014 (2014), pp.1-15.
https://search.emarefa.net/detail/BIM-1042643
American Medical Association (AMA)
Pinazo-Duran, Maria Dolores& Gómez-Ulla, Francisco& Arias, L.& Araiz, Javier& Casaroli-Marano, Ricardo& Gallego-Pinazo, Roberto…[et al.]. Do Nutritional Supplements Have a Role in Age Macular Degeneration Prevention?. Journal of Ophthalmology. 2014. Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-1042643
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1042643