Whole Body Bone Tissue and Cardiovascular Risk in Rheumatoid Arthritis
Joint Authors
Opriş, Daniela
Popescu, Claudiu
Bojincă, Violeta
Ionescu, Ruxandra
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-07
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Introduction.
Atherosclerosis and osteoporosis share an age-independent bidirectional correlation.
Rheumatoid arthritis (RA) represents a risk factor for both conditions.
Objectives.
The study aims to evaluate the connection between the estimated cardiovascular risk (CVR) and the loss of bone tissue in RA patients.
Methods.
The study has a prospective cross-sectional design and it includes female in-patients with RA or without autoimmune diseases; bone tissue was measured using whole body dual X-ray absorptiometry (wbDXA); CVR was estimated using SCORE charts and PROCAM applications.
Results.
There were 75 RA women and 66 normal women of similar age.
The wbDXA bone indices correlate significantly, negatively, and age-independently with the estimated CVR.
The whole body bone percent (wbBP) was a significant predictor of estimated CVR, explaining 26% of SCORE variation along with low density lipoprotein ( P < 0.001 ) and 49.7% of PROCAM variation along with glycemia and menopause duration ( P < 0.001 ).
Although obese patients had less bone relative to body composition (wbBP), in terms of quantity their bone content was significantly higher than that of nonobese patients.
Conclusions.
Female patients with RA and female patients with cardiovascular morbidity have a lower whole body bone percent.
Obese female individuals have higher whole body bone mass than nonobese patients.
American Psychological Association (APA)
Popescu, Claudiu& Bojincă, Violeta& Opriş, Daniela& Ionescu, Ruxandra. 2014. Whole Body Bone Tissue and Cardiovascular Risk in Rheumatoid Arthritis. Journal of Osteoporosis،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1042695
Modern Language Association (MLA)
Popescu, Claudiu…[et al.]. Whole Body Bone Tissue and Cardiovascular Risk in Rheumatoid Arthritis. Journal of Osteoporosis No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1042695
American Medical Association (AMA)
Popescu, Claudiu& Bojincă, Violeta& Opriş, Daniela& Ionescu, Ruxandra. Whole Body Bone Tissue and Cardiovascular Risk in Rheumatoid Arthritis. Journal of Osteoporosis. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1042695
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1042695