Revisiting the Role of First Trimester Homocysteine as an Index of Maternal and Fetal Outcome
Joint Authors
Habeebullah, S.
Mascarenhas, Mariano
Sridhar, M. G.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-05
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Aim.
To revisit the role of first trimester homocysteine levels with the maternal and fetal outcome.
Methods.
This was a cohort study comprising 100 antenatal women between 8 and 12 weeks of gestation.
Serum homocysteine levels were checked after overnight fasting.
Results.
There were significantly elevated homocysteine levels among women with prior history of hypertensive disorders of pregnancy and prior second or third trimester pregnancy losses.
There was no significant difference in homocysteine levels among women with previous gestational diabetes mellitus, preterm deliveries, or fetal malformations.
Homocysteine levels were significantly elevated in those who developed hypertensive disorder of pregnancy, oligohydramnios, and meconium stained amniotic fluid, had a pregnancy loss, or delivered a low birth weight baby.
There was no significant difference in homocysteine levels for those who developed gestational diabetes mellitus.
Conclusions.
Increased first trimester serum homocysteine is associated with history of pregnancy losses, hypertensive disorders of pregnancy, and preterm birth.
This is also associated with hypertensive disorders of pregnancy, pregnancy loss, oligohydramnios, meconium stained amniotic fluid, and low birth weight in the current pregnancy.
This trial is registered with ClinicalTrials.gov CTRI/2013/02/003441.
American Psychological Association (APA)
Mascarenhas, Mariano& Habeebullah, S.& Sridhar, M. G.. 2014. Revisiting the Role of First Trimester Homocysteine as an Index of Maternal and Fetal Outcome. Journal of Pregnancy،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1042710
Modern Language Association (MLA)
Mascarenhas, Mariano…[et al.]. Revisiting the Role of First Trimester Homocysteine as an Index of Maternal and Fetal Outcome. Journal of Pregnancy No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1042710
American Medical Association (AMA)
Mascarenhas, Mariano& Habeebullah, S.& Sridhar, M. G.. Revisiting the Role of First Trimester Homocysteine as an Index of Maternal and Fetal Outcome. Journal of Pregnancy. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1042710
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1042710