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Using Celecoxib for the Suppression of Preterm Labor Instead of Magnesium Sulfate
Joint Authors
Saadati, Najmieh
Moramezi, Farideh
Sokhray, Laila
Cheraghi, Maria
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-10-23
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
We aimed to use celecoxib to suppress preterm labor instead magnesium sulfate (MgSO4) to prevent preterm labor.
Methods.
It was a randomized clinical trial study, which was done on 600 pregnant women.
All subjects were divided into two groups by simple random sampling.
One group was given 4 grams of MgSO4 intravenously and second group was given 100 mg of celecoxib orally every 12 hours for at least 2 days.
The data were entered and analyzed using SPSS 11 and performed using t -test and chi-square test.
Results.
The finding of this study has shown that preterm labor may be prevented in 75.7% of subjects who had received celecoxib and there were no significant difference between two groups in frequency of history of preterm labor ( P = 1 ), frequencies of nulliparity ( P = 0.99 ), duration of drug use and arrest contraction ( P = 0.29 ), delivery before 48 hours ( P = 0.20 ), and mean gestational age in lack of response to treatment ( P = 0.24 ).
Conclusions.
Result has shown that celecoxib was similar to MgSO4 as a medication to prevent preterm labor; it was recommended to be prescribe to prevent preterm labor, because it was cheaper than magnesium sulfate.
American Psychological Association (APA)
Saadati, Najmieh& Moramezi, Farideh& Cheraghi, Maria& Sokhray, Laila. 2014. Using Celecoxib for the Suppression of Preterm Labor Instead of Magnesium Sulfate. Journal of Pregnancy،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1042735
Modern Language Association (MLA)
Saadati, Najmieh…[et al.]. Using Celecoxib for the Suppression of Preterm Labor Instead of Magnesium Sulfate. Journal of Pregnancy No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-1042735
American Medical Association (AMA)
Saadati, Najmieh& Moramezi, Farideh& Cheraghi, Maria& Sokhray, Laila. Using Celecoxib for the Suppression of Preterm Labor Instead of Magnesium Sulfate. Journal of Pregnancy. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-1042735
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1042735