Maternal Opioid Drug Use during Pregnancy and Its Impact on Perinatal Morbidity, Mortality, and the Costs of Medical Care in the United States
Joint Authors
Salemi, Jason L.
Mogos, Mulubrhan F.
Cain, Mary Ashley
Salihu, Hamisu M.
Aliyu, Muktar H.
Whiteman, Valerie
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objective.
To identify factors associated with opioid use during pregnancy and to compare perinatal morbidity, mortality, and healthcare costs between opioid users and nonusers.
Methods.
We conducted a cross-sectional analysis of pregnancy-related discharges from 1998 to 2009 using the largest publicly available all-payer inpatient database in the United States.
We scanned ICD-9-CM codes for opioid use and perinatal outcomes.
Costs of care were estimated from hospital charges.
Survey logistic regression was used to assess the association between maternal opioid use and each outcome; generalized linear modeling was used to compare hospitalization costs by opioid use status.
Results.
Women who used opioids during pregnancy experienced higher rates of depression, anxiety, and chronic medical conditions.
After adjusting for confounders, opioid use was associated with increased odds of threatened preterm labor, early onset delivery, poor fetal growth, and stillbirth.
Users were four times as likely to have a prolonged hospital stay and were almost four times more likely to die before discharge.
The mean per-hospitalization cost of a woman who used opioids during pregnancy was $5,616 (95% CI: $5,166–$6,067), compared to $4,084 (95% CI: $4,002–$4,166) for nonusers.
Conclusion.
Opioid use during pregnancy is associated with adverse perinatal outcomes and increased healthcare costs.
American Psychological Association (APA)
Whiteman, Valerie& Salemi, Jason L.& Mogos, Mulubrhan F.& Cain, Mary Ashley& Aliyu, Muktar H.& Salihu, Hamisu M.. 2014. Maternal Opioid Drug Use during Pregnancy and Its Impact on Perinatal Morbidity, Mortality, and the Costs of Medical Care in the United States. Journal of Pregnancy،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1042737
Modern Language Association (MLA)
Whiteman, Valerie…[et al.]. Maternal Opioid Drug Use during Pregnancy and Its Impact on Perinatal Morbidity, Mortality, and the Costs of Medical Care in the United States. Journal of Pregnancy No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1042737
American Medical Association (AMA)
Whiteman, Valerie& Salemi, Jason L.& Mogos, Mulubrhan F.& Cain, Mary Ashley& Aliyu, Muktar H.& Salihu, Hamisu M.. Maternal Opioid Drug Use during Pregnancy and Its Impact on Perinatal Morbidity, Mortality, and the Costs of Medical Care in the United States. Journal of Pregnancy. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1042737
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1042737