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Six Years of Experience in Photodynamic Therapy for Basal Cell Carcinoma: Results and Fluorescence Diagnosis from 191 Lesions
Joint Authors
Fernández-Guarino, M.
Pérez-García, B.
Royuela, A.
Jaén, P.
Harto, A.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Photodynamic therapy (PDT) has become a therapeutic option for basal cell carcinoma (BCC) in the last decade.
Objectives.
To study the results and predictors of BCC response to treatment with PDT and to evaluate fluorescence diagnosis of BCC.
Methods.
A descriptive, retrospective, and observational study was carried out.
Patients with biopsy-confirmed BCC who were treated with methyl aminolevulinate and red light according to standard treatment protocols (2 sessions separated by 2 weeks, 630 nm, 37 J/cm2, 8 minutes, Aktilite) were selected.
Response was scored as clinically complete and incomplete and the patients were followed up every three months.
Results.
Data from 191 BCC in 181 patients with a mean age of 69.55 years and a mean follow-up period of 34.4 months were collected.
The overall response was 74% of the BCC treated, with the best response in superficial BCC with a 95% of complete response.
The regression analysis revealed that the superficial histological type was the primary factor predictive of a complete response.
Conclusions.
In the treatment of BCC with PDT, the most significant factor for predicting response is the histological type.
American Psychological Association (APA)
Fernández-Guarino, M.& Harto, A.& Pérez-García, B.& Royuela, A.& Jaén, P.. 2014. Six Years of Experience in Photodynamic Therapy for Basal Cell Carcinoma: Results and Fluorescence Diagnosis from 191 Lesions. Journal of Skin Cancer،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1043039
Modern Language Association (MLA)
Fernández-Guarino, M.…[et al.]. Six Years of Experience in Photodynamic Therapy for Basal Cell Carcinoma: Results and Fluorescence Diagnosis from 191 Lesions. Journal of Skin Cancer No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1043039
American Medical Association (AMA)
Fernández-Guarino, M.& Harto, A.& Pérez-García, B.& Royuela, A.& Jaén, P.. Six Years of Experience in Photodynamic Therapy for Basal Cell Carcinoma: Results and Fluorescence Diagnosis from 191 Lesions. Journal of Skin Cancer. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1043039
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1043039