The Hypothalamic-Pituitary-Thyroid Axis in Infants and Children: Protection from Radioiodines
Joint Authors
Yang, Xiaoxia
Harris, Curtis
Koturbash, Igor
Lumen, Annie
Fisher, Jeffrey
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-25
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Potassium iodide (KI) is recommended as an emergency treatment for exposure to radioiodines, most commonly associated with nuclear detonation or mishaps at nuclear power plants.
Protecting the thyroid gland of infants and children remains a priority because of increased incidence of thyroid cancer in the young exposed to radioiodines (such as 131I and 133I).
There is a lack of clinical studies for KI and radioiodines in children or infants to draw definitive conclusions about the effectiveness and safety of KI administration in the young.
In this paper, we compare functional aspects of the hypothalamic-pituitary-thyroid (HPT) axis in the young and adults and review the limited studies of KI in children.
The HPT axis in the infant and child is hyperactive and therefore will respond less effectively to KI treatment compared to adults.
Research on the safety and efficacy of KI in infants and children is needed.
American Psychological Association (APA)
Fisher, Jeffrey& Yang, Xiaoxia& Harris, Curtis& Koturbash, Igor& Lumen, Annie. 2014. The Hypothalamic-Pituitary-Thyroid Axis in Infants and Children: Protection from Radioiodines. Journal of Thyroid Research،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1043269
Modern Language Association (MLA)
Fisher, Jeffrey…[et al.]. The Hypothalamic-Pituitary-Thyroid Axis in Infants and Children: Protection from Radioiodines. Journal of Thyroid Research No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-1043269
American Medical Association (AMA)
Fisher, Jeffrey& Yang, Xiaoxia& Harris, Curtis& Koturbash, Igor& Lumen, Annie. The Hypothalamic-Pituitary-Thyroid Axis in Infants and Children: Protection from Radioiodines. Journal of Thyroid Research. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1043269
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1043269