Evidence for the Gut Microbiota Short-Chain Fatty Acids as Key Pathophysiological Molecules Improving Diabetes
Joint Authors
Montecucco, Fabrizio
Puddu, Alessandra
Sanguineti, Roberta
Viviani, Giorgio Luciano
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-17
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
In type 2 diabetes, hyperglycemia, insulin resistance, increased inflammation, and oxidative stress were shown to be associated with the progressive deterioration of beta-cell function and mass.
Short-chain fatty acids (SCFAs) are organic fatty acids produced in the distal gut by bacterial fermentation of macrofibrous material that might improve type 2 diabetes features.
Their main beneficial activities were identified in the decrease of serum levels of glucose, insulin resistance as well as inflammation, and increase in protective Glucagon-like peptide-1 (GLP-1) secretion.
In this review, we updated evidence on the effects of SCFAs potentially improving metabolic control in type 2 diabetes.
American Psychological Association (APA)
Puddu, Alessandra& Sanguineti, Roberta& Montecucco, Fabrizio& Viviani, Giorgio Luciano. 2014. Evidence for the Gut Microbiota Short-Chain Fatty Acids as Key Pathophysiological Molecules Improving Diabetes. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1043349
Modern Language Association (MLA)
Puddu, Alessandra…[et al.]. Evidence for the Gut Microbiota Short-Chain Fatty Acids as Key Pathophysiological Molecules Improving Diabetes. Mediators of Inflammation No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1043349
American Medical Association (AMA)
Puddu, Alessandra& Sanguineti, Roberta& Montecucco, Fabrizio& Viviani, Giorgio Luciano. Evidence for the Gut Microbiota Short-Chain Fatty Acids as Key Pathophysiological Molecules Improving Diabetes. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1043349
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1043349