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Interferons and Interferon Regulatory Factors in Malaria
Joint Authors
Gun, Sin Yee
Claser, Carla
Rénia, Laurent
Tan, Kevin S. W.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-21, 21 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-15
Country of Publication
Egypt
No. of Pages
21
Main Subjects
Abstract EN
Malaria is one of the most serious infectious diseases in humans and responsible for approximately 500 million clinical cases and 500 thousand deaths annually.
Acquired adaptive immune responses control parasite replication and infection-induced pathologies.
Most infections are clinically silent which reflects on the ability of adaptive immune mechanisms to prevent the disease.
However, a minority of these can become severe and life-threatening, manifesting a range of overlapping syndromes of complex origins which could be induced by uncontrolled immune responses.
Major players of the innate and adaptive responses are interferons.
Here, we review their roles and the signaling pathways involved in their production and protection against infection and induced immunopathologies.
American Psychological Association (APA)
Gun, Sin Yee& Claser, Carla& Tan, Kevin S. W.& Rénia, Laurent. 2014. Interferons and Interferon Regulatory Factors in Malaria. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-21.
https://search.emarefa.net/detail/BIM-1043398
Modern Language Association (MLA)
Gun, Sin Yee…[et al.]. Interferons and Interferon Regulatory Factors in Malaria. Mediators of Inflammation No. 2014 (2014), pp.1-21.
https://search.emarefa.net/detail/BIM-1043398
American Medical Association (AMA)
Gun, Sin Yee& Claser, Carla& Tan, Kevin S. W.& Rénia, Laurent. Interferons and Interferon Regulatory Factors in Malaria. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-21.
https://search.emarefa.net/detail/BIM-1043398
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1043398