The Physiopathological Role of IL-33: New Highlights in Bone Biology and a Proposed Role in Periodontal Disease
Joint Authors
Silva, Marcelo José Barbosa
Cordero da Luz, Felipe Andrés
Lima Oliveira, Ana Paula
Borges, Daniella
Cristina Brígido, Paula
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-18
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Interleukin-33 (IL-33) is a recently described member of the IL-1 family.
IL-33 acts as an alarmin, chemoattractant, and nuclear factor.
ST2, a member of the Toll-like receptor/IL-1R superfamily, the receptor of IL-33, triggers a plethora of downstream effectors and leads the activation of NFK-B, leading the expression of several genes.
IL-33 and ST2 are expressed in the majority of cell types, and the IL-33/ST2 axis has a role in immune response, bone homeostasis, and osteoclastogenesis.
Several studies show opposite roles of IL-33 in osteoclastogenesis and the implication in bone biology.
Few works studied the role of IL-33 in periodontal disease, but we hypothesize a possible role of IL-33 in periodontal disease and bone loss.
American Psychological Association (APA)
Cordero da Luz, Felipe Andrés& Lima Oliveira, Ana Paula& Borges, Daniella& Cristina Brígido, Paula& Silva, Marcelo José Barbosa. 2014. The Physiopathological Role of IL-33: New Highlights in Bone Biology and a Proposed Role in Periodontal Disease. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1043492
Modern Language Association (MLA)
Cordero da Luz, Felipe Andrés…[et al.]. The Physiopathological Role of IL-33: New Highlights in Bone Biology and a Proposed Role in Periodontal Disease. Mediators of Inflammation No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1043492
American Medical Association (AMA)
Cordero da Luz, Felipe Andrés& Lima Oliveira, Ana Paula& Borges, Daniella& Cristina Brígido, Paula& Silva, Marcelo José Barbosa. The Physiopathological Role of IL-33: New Highlights in Bone Biology and a Proposed Role in Periodontal Disease. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1043492
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1043492
