![](/images/graphics-bg.png)
Predictive Factors of Response to Biological Disease Modifying Antirheumatic Drugs: Towards Personalized Medicine
Joint Authors
Daïen, Claire I.
Morel, Jacques
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-12
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Many therapies are now available for patients with rheumatoid arthritis (RA) who have an inadequate response to methotrexate including tumor necrosis factor inhibitors, abatacept, tocilizumab, and rituximab.
Clinical response to drugs varies widely between individuals.
A part of this variability is due to the characteristics of the patient such as age, gender, concomitant therapies, body mass index, or smoking status.
Clinical response also depends on disease characteristics including disease activity and severity and presence of autoantibodies.
Genetic background, cytokine levels, and immune cell phenotypes could also influence biological therapy response.
This review summarizes the impact of all those parameters on response to biological therapies.
American Psychological Association (APA)
Daïen, Claire I.& Morel, Jacques. 2014. Predictive Factors of Response to Biological Disease Modifying Antirheumatic Drugs: Towards Personalized Medicine. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1043526
Modern Language Association (MLA)
Daïen, Claire I.& Morel, Jacques. Predictive Factors of Response to Biological Disease Modifying Antirheumatic Drugs: Towards Personalized Medicine. Mediators of Inflammation No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1043526
American Medical Association (AMA)
Daïen, Claire I.& Morel, Jacques. Predictive Factors of Response to Biological Disease Modifying Antirheumatic Drugs: Towards Personalized Medicine. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1043526
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1043526